| Literature DB >> 8988603 |
P Jain1, H M Garraffo, H J Yeh, T F Spande, J W Daly, N R Andriamaharavo, M Andriantsiferana.
Abstract
A major alkaloid, 217A, in skin extracts of a mantelline frog (Mantella baroni) was isolated by HPLC and the structure defined by 1H-NMR spectral analysis as (1R,4S,10S)- or (1R,4R,10R)- 1-methyl-4-(Z)-(1-pent-2-en-4-ynyl) quinolizidine (1). Four other alkaloids-207I (2), 231A (3), 233A (4), and 235E' (5)-detected in frog skin extracts are proposed to be 1,4-disubstituted quinolizidines based on diagnostic mass and FTIR spectra.Entities:
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Year: 1996 PMID： 8988603 DOI： 10.1021/np9605100
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050