Literature DB >> 8988264

Suicide attempts, age and duration of illness in recurrent affective disorders.

B Ahrens1, A Berghöfer, T Wolf, B Müller-Oerlinghausen.   

Abstract

One of the strongest predictors of suicide is a suicide attempt in the history of the patient. The question, however, is to what extent age and duration of the illness affects the risk of a suicide attempt. In this study, we examined the course of 310 patients with primary affective disorders before lithium prophylaxis and compared the clinical data of those with and without suicide attempts in their history. In a subgroup of 98 patients with suicide attempts, measures for both suicide attempts and inpatient episodes were investigated. Comparing patients with suicide attempts and those without, we found no difference between duration of illness and number of previous episodes between the two groups. However, those with a suicide attempt in their history had an earlier onset of the illness. In the group of 98 suicide attempters, we found no significant correlation between age and rates for both episodes and suicide attempts, which indicates that these rates were not declining as the illness progressed and the patient aged. Dividing the sample into three different age groups, episode rates and rates of attempted suicide were found to be positively correlated in all age groups, again indicating that as long as episodes occur, the suicide risk does not decline. The results are not in favor of findings which suggest that the risk of attempting suicide might manifest itself primarily in the early course of the illness or that suicide attempts in the early course of illness provide a 'cathartic effect' which leads to a lower risk in the later course of the illness. Rather, the findings support the view that the risk of suicide attempts in recurrent affective disorders is unchanged in all age groups and throughout all stages of untreated illness.

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Year:  1995        PMID: 8988264     DOI: 10.1016/0165-0327(95)00054-2

Source DB:  PubMed          Journal:  J Affect Disord        ISSN: 0165-0327            Impact factor:   4.839


  5 in total

1.  Repetition of suicide attempts across episodes of severe depression. Behavioural sensitisation found in suicide group but not in controls.

Authors:  Louise Brådvik; Mats Berglund
Journal:  BMC Psychiatry       Date:  2011-01-07       Impact factor: 3.630

Review 2.  Costs of bipolar disorder.

Authors:  Leah Kleinman; Ana Lowin; Emuella Flood; Gian Gandhi; Eric Edgell; Dennis Revicki
Journal:  Pharmacoeconomics       Date:  2003       Impact factor: 4.981

3.  Suicidal Career in Severe Depression among Long-Term Survivors: In a Followup after 37-53 Years Suicide Attempts Appeared to End Long before Depression.

Authors:  Lisa Crona; Alexander Mossberg; Louise Brådvik
Journal:  Depress Res Treat       Date:  2013-12-23

4.  The association of clinical correlates, metabolic parameters, and thyroid hormones with suicide attempts in first-episode and drug-naïve patients with major depressive disorder comorbid with anxiety: a large-scale cross-sectional study.

Authors:  Yongjie Zhou; Wenchao Ren; Qianqian Sun; Katherine M Yu; Xiaoe Lang; Zezhi Li; Xiang Yang Zhang
Journal:  Transl Psychiatry       Date:  2021-02-04       Impact factor: 7.989

5.  Sequence Analysis of Drug Target Genes with Suicidal Behavior in Bipolar Disorder Patients.

Authors:  Clement C Zai; Arun K Tiwari; Gwyneth C Zai; Vincenzo de Luca; Sajid A Shaikh; Nicole King; John Strauss; James L Kennedy; John B Vincent
Journal:  Mol Neuropsychiatry       Date:  2018-05-03
  5 in total

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