| Literature DB >> 8987394 |
Abstract
The tyrosine and dual-specificity phosphatases are involved in signaling, cell growth and differentiation, and the cell cycle. The enzymes share a common catalytic mechanism mediated by an active site cysteine, arginine and aspartic acid. Supplementary domains assist in targeting and substrate specificity.Entities:
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Year: 1996 PMID： 8987394 DOI： 10.1016/s0968-0004(96)10059-1
Source DB: PubMed Journal: Trends Biochem Sci ISSN： 0968-0004 Impact factor: 13.807