Literature DB >> 8985145

Complete synthesis of 3'-sialyl-N-acetyllactosamine by regioselective transglycosylation.

A Vetere1, S Paoletti.   

Abstract

Transglycolytic synthesis of 3'-sialyl-N-acetyllactosamine by sequential use of beta-galactosidase from Bacillus circulans and trans-sialidase from Trypanosoma cruzi was described. These reactions depicted the first complete synthesis of a biologically important oligosaccharide with high regioselectivity avoiding use of glycosyltransferases and NDP sugars.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 8985145     DOI： 10.1016/s0014-5793(96)01267-7

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  3 in total

1.  Identification by saturation mutagenesis of a single residue involved in the alpha-galactosidase AgaB regioselectivity.

Authors:  M Dion; G Osanjo; C André; P Spangenberg; C Rabiller; C Tellier
Journal:  Glycoconj J       Date:  2001-06       Impact factor: 2.916

2.  Modulation of the regioselectivity of a Bacillus alpha-galactosidase by directed evolution.

Authors:  M Dion; A Nisole; P Spangenberg; C André; A Glottin-Fleury; R Mattes; C Tellier; C Rabiller
Journal:  Glycoconj J       Date:  2001-03       Impact factor: 2.916

Review 3.  trans-Sialylation: a strategy used to incorporate sialic acid into oligosaccharides.

Authors:  Rosa M de Lederkremer; María Eugenia Giorgi; Rosalía Agusti
Journal:  RSC Chem Biol       Date:  2021-11-23
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.