Literature DB >> 8984148

Cytotoxic oxygenated desmosterols of the red alga Galaxaura marginata.

J H Sheu1, S Y Huang, C Y Duh.   

Abstract

Desmosterol (1), 24,25-epoxycholesterol (2), 24-hydroperoxycholesta-5,25-dien-3 beta-ol (3), 25-hydroperoxycholesta-5,23(E)-dien-3 beta-ol (4), cholesta-5,25-diene-3 beta,24-diol (5), and 24,25-epoxy-6 beta-hydroxycholest-4-en-3-one (7) were isolated from the marine red alga Galaxaura marginata; sterols 3, 4, and 7 were isolated for the first time from a natural source. Sterols 3-7 exhibited significant cytotoxicity toward several cancer cell lines.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 8984148     DOI： 10.1021/np960016w

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  6 in total

1.  Acute toxicity study and antipyretic effect of the brown alga Turbinaria conoides (J. Agardh) Kuetz.

Authors:  S Sadish Kumar; Y Kumar; M S Y Khan; J Anbu; K G Sam
Journal:  Afr J Tradit Complement Altern Med       Date:  2009-05-07

2.  New cytotoxic oxygenated sterols from the marine bryozoan Cryptosula pallasiana.

Authors:  Xiang-Rong Tian; Hai-Feng Tang; Yu-Shan Li; Hou-Wen Lin; Xiao-Li Chen; Ning Ma; Min-Na Yao; Ping-Hu Zhang
Journal:  Mar Drugs       Date:  2011-01-28       Impact factor: 6.085

3.  Antimicrobial and cytotoxic activities of turbinariaconoides (j.agardh) kuetz.

Authors:  Sadish Kumar Shanmugam; Yatendra Kumar; Khan Mohammad Sardaryar; Vivek Gupta; Erik De Clercq
Journal:  Iran J Pharm Res       Date:  2010       Impact factor: 1.696

4.  Bioactive chemical constituents from the brown alga Homoeostrichus formosana.

Authors:  Hui-Yu Fang; Uvarani Chokkalingam; Shu-Fen Chiou; Tsong-Long Hwang; Shu-Li Chen; Wei-Lung Wang; Jyh-Horng Sheu
Journal:  Int J Mol Sci       Date:  2014-12-30       Impact factor: 5.923

5.  An In silico Based Comparison of Drug Interactions in Wild and Mutant Human β-tubulin through Docking Studies.

Authors:  Selvaakumar Chellasamy; Sudheer M M Mohammed
Journal:  Avicenna J Med Biotechnol       Date:  2014-04

Review 6.  The Use of Invasive Algae Species as a Source of Secondary Metabolites and Biological Activities: Spain as Case-Study.

Authors:  Antia G Pereira; Maria Fraga-Corral; Paula Garcia-Oliveira; Catarina Lourenço-Lopes; Maria Carpena; Miguel A Prieto; Jesus Simal-Gandara
Journal:  Mar Drugs       Date:  2021-03-24       Impact factor: 5.118
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.