Literature DB >> 8983964

Characterization of alpha 2-adrenoceptor subtypes in the porcine eye: identification of alpha 2A-adrenoceptors in the choroid, ciliary body and iris, and alpha 2A- and alpha 2C-adrenoceptors in the retina.

A Wikberg-Matsson1, J E Wikberg, S Uhlén.   

Abstract

The subtypes of alpha 2-adrenoceptor were characterized in the choroid, ciliary body, iris and retina of the pig eye by using radioligand binding. [3H]-MK912 labelled dense populations of alpha 2A-adrenoceptors in the choroid and ciliary body. In the retina, [3H]-MK912 labelled both alpha 2A- and alpha 2C-adrenoceptors. In the iris, receptors of the alpha 2A-adrenoceptor type were detected by using either [3H]-MK912 or [3H]-RX821002 as radioligands.

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Year:  1996        PMID: 8983964     DOI: 10.1006/exer.1996.0091

Source DB:  PubMed          Journal:  Exp Eye Res        ISSN: 0014-4835            Impact factor:   3.467


  4 in total

1.  Detection of cannabinoid CB1, adenosine A1, muscarinic acetylcholine, and GABA(B) receptor-dependent G protein activity in transducin-deactivated membranes and autoradiography sections of rat retina.

Authors:  Juha R Savinainen; Jarmo T Laitinen
Journal:  Cell Mol Neurobiol       Date:  2004-04       Impact factor: 5.046

2.  Topical mydriatics affect light-evoked retinal responses in anesthetized mice.

Authors:  Deb Kumar Mojumder; Theodore G Wensel
Journal:  Invest Ophthalmol Vis Sci       Date:  2009-08-06       Impact factor: 4.799

Review 3.  Human ganglion cells express the alpha-2 adrenergic receptor: relevance to neuroprotection.

Authors:  F B Kalapesi; M T Coroneo; M A Hill
Journal:  Br J Ophthalmol       Date:  2005-06       Impact factor: 4.638

4.  Prejunctional alpha2-adrenoceptors and peroxide-induced potentiation of norepinephrine release from the bovine iris.

Authors:  C A Opere; S E Ohia
Journal:  Neurochem Res       Date:  1998-08       Impact factor: 3.996

  4 in total

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