Literature DB >> 8982711

A genetic mouse model of helplessness sensitive to imipramine.

J M Vaugeois1, C Odièvre, L Loisel, J Costentin.   

Abstract

Lines of mice were selectively bred to diverge in their spontaneous helplessness in the tail suspension test. By the second generation of selection, only mice of the helpless line were sensitive to the antidepressant imipramine. Genetic factors substantially contribute to the susceptibility to helplessness in this mouse model. These selectively bred lines may represent potentially useful animal models to investigate behavioural, neurochemical and neuroendocrine correlates of antidepressant action.

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Year:  1996        PMID： 8982711     DOI： 10.1016/s0014-2999(96)00800-x

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  8 in total

1.  A prescription to resist proscriptions for murine models of depression.

Authors:  I Lucki
Journal:  Psychopharmacology (Berl)       Date:  2001-01       Impact factor: 4.530

2.  Adenosine A2A receptor antagonists are potential antidepressants: evidence based on pharmacology and A2A receptor knockout mice.

Authors:  M El Yacoubi; C Ledent; M Parmentier; R Bertorelli; E Ongini; J Costentin; J M Vaugeois
Journal:  Br J Pharmacol       Date:  2001-09       Impact factor: 8.739

3.  cAMP response element-binding protein is essential for the upregulation of brain-derived neurotrophic factor transcription, but not the behavioral or endocrine responses to antidepressant drugs.

Authors:  Alana C Conti; John F Cryan; Ashutosh Dalvi; Irwin Lucki; Julie A Blendy
Journal:  J Neurosci       Date:  2002-04-15       Impact factor: 6.167

4.  Behavioral, neurochemical, and electrophysiological characterization of a genetic mouse model of depression.

Authors:  Malika El Yacoubi; Saoussen Bouali; Daniela Popa; Laurent Naudon; Isabelle Leroux-Nicollet; Michel Hamon; Jean Costentin; Joëlle Adrien; Jean-Marie Vaugeois
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-05       Impact factor: 11.205

5.  Deletion of fibroblast growth factor 22 (FGF22) causes a depression-like phenotype in adult mice.

Authors:  Aislinn J Williams; Patricia Yee; Mitchell C Smith; Geoffrey G Murphy; Hisashi Umemori
Journal:  Behav Brain Res       Date:  2016-03-29       Impact factor: 3.332

6.  RGS2 drives male aggression in mice via the serotonergic system.

Authors:  Melanie D Mark; Patric Wollenweber; Annika Gesk; Katja Kösters; Katharina Batzke; Claudia Janoschka; Takashi Maejima; Jing Han; Evan S Deneris; Stefan Herlitze
Journal:  Commun Biol       Date:  2019-10-11

7.  Quantitative traits for the tail suspension test: automation, optimization, and BXD RI mapping.

Authors:  Heena V Lad; Lin Liu; José L Payá-Cano; Cathy Fernandes; Leonard C Schalkwyk
Journal:  Mamm Genome       Date:  2007-07-07       Impact factor: 2.957

Review 8.  The Role of Muscarinic Receptors in the Pathophysiology of Mood Disorders: A Potential Novel Treatment?

Authors:  Won Je Jeon; Brian Dean; Elizabeth Scarr; Andrew Gibbons
Journal:  Curr Neuropharmacol       Date:  2015       Impact factor: 7.363
  8 in total

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