Literature DB >> 8982255

Cloning and functional characterization of a rat urea transporter: expression in the brain.

C Couriaud1, P Ripoche, G Rousselet.   

Abstract

A cDNA coding for a rat urea transporter is described. The 1242 bp open reading frame codes for a 414 amino acids protein with 77.0% and 60.7% identity with the human UT11 and the rat UT2, respectively. When expressed in Xenopus oocytes, the protein induces a 10-fold rise in urea permeability, inhibited by mercurial reagents and phloretin. The rUT11 mRNA is massively expressed in the brain.

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Year:  1996        PMID： 8982255     DOI： 10.1016/s0167-4781(96)00172-8

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  7 in total

Review 1.  The erythrocyte urea transporter UT-B.

Authors:  Serena M Bagnasco
Journal:  J Membr Biol       Date:  2007-01-30       Impact factor: 1.843

Review 2.  Role and regulation of urea transporters.

Authors:  Serena M Bagnasco
Journal:  Pflugers Arch       Date:  2005-05-28       Impact factor: 3.657

3.  The Helicobacter pylori VacA toxin is a urea permease that promotes urea diffusion across epithelia.

Authors:  F Tombola; L Morbiato; G Del Giudice; R Rappuoli; M Zoratti; E Papini
Journal:  J Clin Invest       Date:  2001-09       Impact factor: 14.808

4.  Developing hypothetical inhibition mechanism of novel urea transporter B inhibitor.

Authors:  Min Li; Weng Ieong Tou; Hong Zhou; Fei Li; Huiwen Ren; Calvin Yu-Chian Chen; Baoxue Yang
Journal:  Sci Rep       Date:  2014-07-22       Impact factor: 4.379

5.  Urea transporter physiology studied in knockout mice.

Authors:  Xuechen Li; Guangping Chen; Baoxue Yang
Journal:  Front Physiol       Date:  2012-06-26       Impact factor: 4.566

6.  Functional inhibition of urea transporter UT-B enhances endothelial-dependent vasodilatation and lowers blood pressure via L-arginine-endothelial nitric oxide synthase-nitric oxide pathway.

Authors:  Yi Sun; Chi-Wai Lau; Yingli Jia; Yingjie Li; Weiling Wang; Jianhua Ran; Fei Li; Yu Huang; Hong Zhou; Baoxue Yang
Journal:  Sci Rep       Date:  2016-01-07       Impact factor: 4.379

7.  The Expression of AQP5 and UTs in the Sweat Glands of Uremic Patients.

Authors:  Liyi Xie; Li Jin; Jie Feng; Jing Lv
Journal:  Biomed Res Int       Date:  2017-11-27       Impact factor: 3.411
  7 in total

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