OBJECTIVE: To report the clinical spectrum of polyarteritis nodosa (PAN) from North India and highlight some unusual findings. DESIGN: Retrospective study. SETTING: Hospital based. SUBJECTS: Eight children with PAN. INTERVENTION: Treatment with prednisolone and cyclophosphamide. RESULTS: One child had spontaneous remission while another started deteriorating rapidly in spite of treatment and died within 2 weeks. Six children went into remission-of these one died, two were lost to follow-up and the remaining three are on regular follow-up for periods ranging from 3-5 years. CONCLUSIONS: Prednisolone and cyclophosphamide can significantly improve the outcome in childhood PAN.
OBJECTIVE: To report the clinical spectrum of polyarteritis nodosa (PAN) from North India and highlight some unusual findings. DESIGN: Retrospective study. SETTING: Hospital based. SUBJECTS: Eight children with PAN. INTERVENTION: Treatment with prednisolone and cyclophosphamide. RESULTS: One child had spontaneous remission while another started deteriorating rapidly in spite of treatment and died within 2 weeks. Six children went into remission-of these one died, two were lost to follow-up and the remaining three are on regular follow-up for periods ranging from 3-5 years. CONCLUSIONS:Prednisolone and cyclophosphamide can significantly improve the outcome in childhood PAN.