Literature DB >> 8978909

Identification of a cDNA encoding 6-phosphogluconate dehydrogenase from a human heart cDNA library.

S K Tsui1, J Y Chan, M M Waye, K P Fung, C Y Lee.   

Abstract

A full-length cDNA clone for human 6-phosphogluconate dehydrogenase (PGD) was isolated from a human adult heart cDNA library. The clone encoded an open reading frame of 483 amino acids. When the amino acid sequences of human PGD and sheep PGD were aligned, 94.2% identity between these two proteins was found. Its calculated molecular weight is 53,149 daltons. The predicted isoelectric point is 6.85. When the secondary structure of human PGD was examined by the PROSIS software, 36% alpha-helix and 9% beta-sheet were found.

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Year:  1996        PMID： 8978909     DOI： 10.1007/bf00554412

Source DB:  PubMed          Journal:  Biochem Genet        ISSN： 0006-2928            Impact factor:   1.890


  13 in total

1.  Basic local alignment search tool.

Authors:  S F Altschul; W Gish; W Miller; E W Myers; D J Lipman
Journal:  J Mol Biol       Date:  1990-10-05       Impact factor: 5.469

2.  Efficient automated large-scale sequencing of unpurified PCR product.

Authors:  S K Tsui; M M Waye; C Y Lee
Journal:  Biotechniques       Date:  1995-10       Impact factor: 1.993

3.  Crystalline 6-phosphogluconate dehydrogenase from sheep liver.

Authors:  M Silverberg; K Dalziel
Journal:  Eur J Biochem       Date:  1973-10-05

4.  A human heart cDNA library--the development of an efficient and simple method for automated DNA sequencing.

Authors:  C C Liew
Journal:  J Mol Cell Cardiol       Date:  1993-08       Impact factor: 5.000

5.  Single pass sequencing of a unidirectional human fetal heart cDNA library to discover novel genes of the cardiovascular system.

Authors:  D M Hwang; W S Hwang; C C Liew
Journal:  J Mol Cell Cardiol       Date:  1994-10       Impact factor: 5.000

6.  A catalogue of genes in the cardiovascular system as identified by expressed sequence tags.

Authors:  C C Liew; D M Hwang; Y W Fung; C Laurenssen; E Cukerman; S Tsui; C Y Lee
Journal:  Proc Natl Acad Sci U S A       Date:  1994-10-25       Impact factor: 11.205

7.  Sheep 6-phosphogluconate dehydrogenase. Revised protein sequence based upon the sequences of cDNA clones obtained with the polymerase chain reaction.

Authors:  D O Somers; S M Medd; J E Walker; M J Adams
Journal:  Biochem J       Date:  1992-12-15       Impact factor: 3.857

8.  A novel cDNA encoding a human homologue of ribosomal protein L29.

Authors:  P T Law; S K Tsui; W Y Lam; S C Luk; D M Hwang; C C Liew; C Y Lee; K P Fung; M M Waye
Journal:  Biochim Biophys Acta       Date:  1996-03-01

9.  Evolutionary inferences from DNA variation at the 6-phosphogluconate dehydrogenase locus in natural populations of drosophila: selection and geographic differentiation.

Authors:  D J Begun; C F Aquadro
Journal:  Genetics       Date:  1994-01       Impact factor: 4.562

10.  The three dimensional structure of sheep liver 6-phosphogluconate dehydrogenase at 2.6 A resolution.

Authors:  M J Adams; I G Archibald; C E Bugg; A Carne; S Gover; J R Helliwell; R W Pickersgill; S W White
Journal:  EMBO J       Date:  1983       Impact factor: 11.598
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  3 in total

1.  Functional constraints of 6-phosphogluconate dehydrogenase (6-PGD) based on sequence and structural information.

Authors:  George N Goulielmos; Elias Eliopoulos; Michael Loukas; Spyros Tsakas
Journal:  J Mol Evol       Date:  2004-09       Impact factor: 2.395

2.  Comparative Approach of the de novo Fatty Acid Synthesis (Lipogenesis) between Ruminant and Non Ruminant Mammalian Species: From Biochemical Level to the Main Regulatory Lipogenic Genes.

Authors:  G P Laliotis; I Bizelis; E Rogdakis
Journal:  Curr Genomics       Date:  2010-05       Impact factor: 2.236

3.  Enzymatic and mRNA Transcript Response of Ovine 6-Phosphogluconate Dehydrogenase (6PGD) in Respect to Different Milk Yield.

Authors:  Stamatina Trivizaki; George P Laliotis; Iosif Bizelis; Maria A Charismiadou; Emmanuel Rogdakis
Journal:  Biochem Res Int       Date:  2009-11-16
  3 in total

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