Literature DB >> 8977721

A new method of intralesional bleomycin therapy in the treatment of recalcitrant warts.

S E Munn1, E Higgins, M Marshall, M Clement.   

Abstract

We have used a new technique of bleomycin injection to treat intractable palmar, plantar and periungual warts. Following local anaesthesia with topical EMLA (lignocaine and prilocaine) cream, 1 mg/ml bleomycin solution was dropped on to the wart and 'pricked' into the wart using a Monolet needle. We achieved 92% success rate which compares well with other authors whose success rates with intralesional bleomycin vary between 33 and 92%. We conclude that this technique of intralesional bleomycin therapy is an effective, safe and generally well tolerated treatment for recalcitrant warts.

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Year:  1996        PMID: 8977721     DOI: 10.1046/j.1365-2133.1996.d01-1104.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN: 0007-0963            Impact factor:   9.302


  7 in total

Review 1.  An armamentarium of wart treatments.

Authors:  Michelle M Lipke
Journal:  Clin Med Res       Date:  2006-12

2.  Efficacy of a bleomycin microneedle patch for the treatment of warts.

Authors:  Ha Ryeong Ryu; Hye-Rin Jeong; Hye-Seung Seon-Woo; Jung Soo Kim; Seul Ki Lee; Hee Joo Kim; Jin Ok Baek; Jung-Hwan Park; Joo Young Roh
Journal:  Drug Deliv Transl Res       Date:  2018-02       Impact factor: 4.617

3.  Dynamics of bleomycin interaction with a strongly bound hairpin DNA substrate, and implications for cleavage of the bound DNA.

Authors:  Trevor C Bozeman; Rupesh Nanjunda; Chenhong Tang; Yang Liu; Zachary J Segerman; Paul A Zaleski; W David Wilson; Sidney M Hecht
Journal:  J Am Chem Soc       Date:  2012-10-22       Impact factor: 15.419

4.  Long-pulsed Nd:YAG laser treatment of warts: report on a series of 369 cases.

Authors:  Tae Young Han; Ji Ho Lee; Chang Kyun Lee; Ji Young Ahn; Seong Jun Seo; Chang Kwun Hong
Journal:  J Korean Med Sci       Date:  2009-09-23       Impact factor: 2.153

5.  Preliminary study of intralesional bleomycin injection for the treatment of genital warts.

Authors:  Jin Yong Lee; Chul Woo Kim; Sang Seok Kim
Journal:  Ann Dermatol       Date:  2015-03-24       Impact factor: 1.444

Review 6.  Advancements in Pharmacotherapy for Noncancerous Manifestations of HPV.

Authors:  Ramya Kollipara; Erfon Ekhlassi; Christopher Downing; Jacqueline Guidry; Michael Lee; Stephen K Tyring
Journal:  J Clin Med       Date:  2015-04-24       Impact factor: 4.241

7.  Topical immunotherapy with diphenylcyclopropenone is effective and preferred in the treatment of periungual warts.

Authors:  Yunseok Choi; Do Hun Kim; Sang Yun Jin; Ai-Young Lee; Seung Ho Lee
Journal:  Ann Dermatol       Date:  2013-11-30       Impact factor: 1.444

  7 in total

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