Literature DB >> 8977547

Epidemiology of malignant melanoma.

T Liu1, S J Soong.   

Abstract

Descriptive epidemiology of melanoma indicates increases in both incidence and mortality over the past two to three decades. A moderation in both rates began to emerge in several regions after the 1980s, especially in younger age groups. Recent improvement in survival rates is more likely due to earlier diagnosis than to real improvement in treatment. This suggests the potential effectiveness of secondary prevention. Continued health education efforts to improve awareness about signs and symptoms of melanoma should lead to earlier diagnosis and may increase incidence for a certain period of time. However, reduction in mortality will eventually be achieved owing to thinner melanoma at time of diagnosis. Etiologic studies indicate that the most important environmental risk factor for melanoma is extensive exposure to the sun. Primary prevention efforts should target public education about the risk of sun exposure and the benefit of wearing hats and adequate clothing. Specific prevention and control programs should be implemented among high-risk groups, such as those with light complexions and those sensitive to sunburn. In view of the long latency of melanoma, as much as 10 years, past exposure to the risk factors continues to cause melanoma, and any benefits of preventive efforts do not appear for some time. Although a dramatic decline is not expected in melanoma rates immediately, continuous preventive efforts ultimately should lead to a reduction in incidence and mortality.

Entities:  

Mesh:

Year:  1996        PMID: 8977547     DOI: 10.1016/s0039-6109(05)70511-9

Source DB:  PubMed          Journal:  Surg Clin North Am        ISSN: 0039-6109            Impact factor:   2.741


  5 in total

1.  Dead cells in melanoma tumors provide abundant antigen for targeted delivery of ionizing radiation by a mAb to melanin.

Authors:  Ekaterina Dadachova; Joshua D Nosanchuk; Li Shi; Andrew D Schweitzer; Annie Frenkel; Jerome S Nosanchuk; Arturo Casadevall
Journal:  Proc Natl Acad Sci U S A       Date:  2004-10-05       Impact factor: 11.205

2.  An Ecological Study Indicates the Importance of Ultraviolet A Protection in Sunscreens.

Authors:  Samar Merhi; Pascale Salameh; Peter Kaplan; Shayak Banerjee; Mohamed Lajnef; Emmanuel L P Dumont; Khaled Ezzedine
Journal:  Acta Derm Venereol       Date:  2021-06-28       Impact factor: 3.875

3.  Oral contraceptive use and risk of melanoma in premenopausal women.

Authors:  D Feskanich; D J Hunter; W C Willett; D Spiegelman; M J Stampfer; F E Speizer; G A Colditz
Journal:  Br J Cancer       Date:  1999-11       Impact factor: 7.640

Review 4.  UV radiation and the skin.

Authors:  John D'Orazio; Stuart Jarrett; Alexandra Amaro-Ortiz; Timothy Scott
Journal:  Int J Mol Sci       Date:  2013-06-07       Impact factor: 5.923

5.  Temporal and spatial melanoma trends in Austria: an ecological study.

Authors:  Daniela Haluza; Stana Simic; Hanns Moshammer
Journal:  Int J Environ Res Public Health       Date:  2014-01-06       Impact factor: 3.390

  5 in total

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