Literature DB >> 8977257

Adult T-cell leukemia/lymphoma on a background of clonally expanding human T-cell leukemia virus type-1-positive cells.

M Cavrois1, S Wain-Hobson, A Gessain, Y Plumelle, E Wattel.   

Abstract

Tumorous and nontumorous samples from patients with various forms of adult T-cell leukemia/lymphoma (ATLL) were analyzed using the sensitive inverse polymerase chain reaction (PCR) technique. In all samples, oligoclonal expansion of human T-cell leukemia virus (HTLV)-1 bearing T cells were detected, even for the tumorous samples that were mainly monoclonal by Southern blotting. For one case of smouldering ATLL, chemotherapy apparently reduced the number of detectable clones. Taken together with similar data on asymptomatic and symptomatic HTLV-1 carriers without malignancy, it would appear that ATLL appears on a prior background of HTLV-1-initiated oligoclonal expansion.

Entities:  

Mesh：

Year:  1996        PMID： 8977257

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  20 in total

1.  Genetic instability of adult T-cell leukemia/lymphoma by comparative genomic hybridization analysis.

Authors:  Kunhiro Tsukasaki
Journal:  J Clin Immunol       Date:  2002-03       Impact factor: 8.317

Review 2.  Animal models for human T-lymphotropic virus type 1 (HTLV-1) infection and transformation.

Authors:  Michael D Lairmore; Lee Silverman; Lee Ratner
Journal:  Oncogene       Date:  2005-09-05       Impact factor: 9.867

3.  HTLV-1 propels untransformed CD4 lymphocytes into the cell cycle while protecting CD8 cells from death.

Authors:  David Sibon; Anne-Sophie Gabet; Marc Zandecki; Christiane Pinatel; Julien Thête; Marie-Hélène Delfau-Larue; Samira Rabaaoui; Antoine Gessain; Olivier Gout; Steven Jacobson; Franck Mortreux; Eric Wattel
Journal:  J Clin Invest       Date:  2006-04       Impact factor: 14.808

4.  Two-step nature of human T-cell leukemia virus type 1 replication in experimentally infected squirrel monkeys (Saimiri sciureus).

Authors:  F Mortreux; M Kazanji; A S Gabet; B de Thoisy; E Wattel
Journal:  J Virol       Date:  2001-01       Impact factor: 5.103

5.  The host genomic environment of the provirus determines the abundance of HTLV-1-infected T-cell clones.

Authors:  Nicolas A Gillet; Nirav Malani; Anat Melamed; Niall Gormley; Richard Carter; David Bentley; Charles Berry; Frederic D Bushman; Graham P Taylor; Charles R M Bangham
Journal:  Blood       Date:  2011-01-12       Impact factor: 22.113

6.  Tax protein-induced expression of antiapoptotic Bfl-1 protein contributes to survival of human T-cell leukemia virus type 1 (HTLV-1)-infected T-cells.

Authors:  Héloïse Macaire; Aurélien Riquet; Vincent Moncollin; Marie-Claude Biémont-Trescol; Madeleine Duc Dodon; Olivier Hermine; Anne-Laure Debaud; Renaud Mahieux; Jean-Michel Mesnard; Marlène Pierre; Louis Gazzolo; Nathalie Bonnefoy; Hélène Valentin
Journal:  J Biol Chem       Date:  2012-05-02       Impact factor: 5.157

7.  Host sequences flanking the human T-cell leukemia virus type 1 provirus in vivo.

Authors:  I Leclercq; F Mortreux; M Cavrois; A Leroy; A Gessain; S Wain-Hobson; E Wattel
Journal:  J Virol       Date:  2000-03       Impact factor: 5.103

8.  In vivo analysis of human T-cell leukemia virus type 1 reverse transcription accuracy.

Authors:  L M Mansky
Journal:  J Virol       Date:  2000-10       Impact factor: 5.103

9.  Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins.

Authors:  S Takemoto; J C Mulloy; A Cereseto; T S Migone; B K Patel; M Matsuoka; K Yamaguchi; K Takatsuki; S Kamihira; J D White; W J Leonard; T Waldmann; G Franchini
Journal:  Proc Natl Acad Sci U S A       Date:  1997-12-09       Impact factor: 11.205

10.  Activation of human T-cell leukemia virus type 1 tax gene expression in chronically infected T cells.

Authors:  H C Lin; C S Dezzutti; R B Lal; A B Rabson
Journal:  J Virol       Date:  1998-07       Impact factor: 5.103
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