Literature DB >> 8976830

Differences in clinical manifestations of genital chlamydial infections related to serovars.

M J van de Laar1, Y T van Duynhoven, J S Fennema, J M Ossewaarde, A J van den Brule, G J van Doornum, R A Coutinho, J A van den Hoek.   

Abstract

OBJECTIVES: To study the association of serovars of Chlamydia trachomatis with clinical manifestations of genital tract infection and socio-demographic characteristics.
METHODS: In 1986-88 the C trachomatis isolates from 159 heterosexual men and 116 women attending a sexually transmitted disease (STD) clinic were collected and typed accordingly. A medical history was recorded, a physical examination took place and samples were taken for laboratory diagnostics.
RESULTS: Serovars E, F and D were the most common for both men (75%) and women (67%). Men infected with serovars of the C-complex had more often a history of STD (p = 0.06). The opposite was demonstrated in women (p = 0.07). In addition, women younger than 18 years at first intercourse were more often infected with C-complex serovars (p = 0.05). For men, the serovars F/G less often produced symptoms of urethral discharge (p = 0.01) than the serovars of the B-complex and C-complex and were less often associated with the presence of 10 or more leukocytes in a Gram-stained smear (p = 0.04).
CONCLUSIONS: In this study, infections with serovars F and G caused less obvious symptoms and signs of inflammation in men; in women no differences were found in the clinical manifestation of infections with different serovars.

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Mesh:

Year:  1996        PMID: 8976830      PMCID: PMC1195674     

Source DB:  PubMed          Journal:  Genitourin Med        ISSN: 0266-4348


  23 in total

1.  Serovar distribution of urogenital Chlamydia trachomatis strains in The Netherlands.

Authors:  J H Wagenvoort; R J Suchland; W E Stamm
Journal:  Genitourin Med       Date:  1988-06

2.  Chlamydia trachomatis immunotypes in Finland.

Authors:  P Saikku; S P Wang
Journal:  Acta Pathol Microbiol Immunol Scand B       Date:  1987-04

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Authors:  J Schachter
Journal:  N Engl J Med       Date:  1978-02-23       Impact factor: 91.245

4.  Comparison of two panels of monoclonal antibodies for determination of Chlamydia trachomatis serovars.

Authors:  J M Ossewaarde; M Rieffe; A de Vries; R P Derksen-Nawrocki; H J Hooft; G J van Doornum; A M van Loon
Journal:  J Clin Microbiol       Date:  1994-12       Impact factor: 5.948

5.  Immunotypes of Chlamydia trachomatis isolates in Seattle, Washington.

Authors:  C C Kuo; S P Wang; K K Holmes; J T Grayston
Journal:  Infect Immun       Date:  1983-08       Impact factor: 3.441

6.  Immunotyping of Chlamydia trachomatis with monoclonal antibodies.

Authors:  S P Wang; C C Kuo; R C Barnes; R S Stephens; J T Grayston
Journal:  J Infect Dis       Date:  1985-10       Impact factor: 5.226

7.  Comparison of Chlamydia trachomatis serovars causing rectal and cervical infections.

Authors:  R C Barnes; A M Rompalo; W E Stamm
Journal:  J Infect Dis       Date:  1987-12       Impact factor: 5.226

8.  Detection of multiple serovars of Chlamydia trachomatis in genital infections.

Authors:  R C Barnes; R J Suchland; S P Wang; C C Kuo; W E Stamm
Journal:  J Infect Dis       Date:  1985-11       Impact factor: 5.226

9.  Chlamydia trachomatis proctitis.

Authors:  T C Quinn; S E Goodell; E Mkrtichian; M D Schuffler; S P Wang; W E Stamm; K K Holmes
Journal:  N Engl J Med       Date:  1981-07-23       Impact factor: 91.245

10.  Development and evaluation of screening strategies for Chlamydia trachomatis infections in an STD clinic.

Authors:  Y T van Duynhoven; M J van de Laar; J S Fennema; G J van Doornum; J A van den Hoek
Journal:  Genitourin Med       Date:  1995-12
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  17 in total

1.  Analysis of genetic heterogeneity in Chlamydia trachomatis clinical isolates of serovars D, E, and F by amplified fragment length polymorphism.

Authors:  S A Morré; J M Ossewaarde; P H Savelkoul; J Stoof; C J Meijer; A J van den Brule
Journal:  J Clin Microbiol       Date:  2000-09       Impact factor: 5.948

2.  Urogenital Chlamydia trachomatis serovars in men and women with a symptomatic or asymptomatic infection: an association with clinical manifestations?

Authors:  S A Morré; L Rozendaal; I G van Valkengoed; A J Boeke; P C van Voorst Vader; J Schirm; S de Blok; J A van Den Hoek; G J van Doornum; C J Meijer; A J van Den Brule
Journal:  J Clin Microbiol       Date:  2000-06       Impact factor: 5.948

3.  Failure to detect Chlamydia trachomatis in cell culture by using a monoclonal antibody directed against the major outer membrane protein.

Authors:  J Boman; C Gaydos; P Juto; G Wadell; T C Quinn
Journal:  J Clin Microbiol       Date:  1997-10       Impact factor: 5.948

4.  Genotyping of Portuguese Chlamydia trachomatis urogenital isolates.

Authors:  M J Borrego; J P Gomes; J F Lefebvre; F Eb; J Orfila; M A Catry
Journal:  Genitourin Med       Date:  1997-12

5.  Evolutionary dynamics of ompA, the gene encoding the Chlamydia trachomatis key antigen.

Authors:  Alexandra Nunes; Maria J Borrego; Baltazar Nunes; Carlos Florindo; João P Gomes
Journal:  J Bacteriol       Date:  2009-09-25       Impact factor: 3.490

6.  Serotyping and genotyping of genital Chlamydia trachomatis isolates reveal variants of serovars Ba, G, and J as confirmed by omp1 nucleotide sequence analysis.

Authors:  S A Morré; J M Ossewaarde; J Lan; G J van Doornum; J M Walboomers; D M MacLaren; C J Meijer; A J van den Brule
Journal:  J Clin Microbiol       Date:  1998-02       Impact factor: 5.948

7.  Analysis of rectal Chlamydia trachomatis serovar distribution including L2 (lymphogranuloma venereum) at the Erasmus MC STI clinic, Rotterdam.

Authors:  R Waalboer; E M van der Snoek; W I van der Meijden; P G H Mulder; J M Ossewaarde
Journal:  Sex Transm Infect       Date:  2006-06       Impact factor: 3.519

8.  Molecular epidemiology of genital Chlamydia trachomatis infection in high-risk women in Senegal, West Africa.

Authors:  K Sturm-Ramirez; H Brumblay; K Diop; A Guèye-Ndiaye; J L Sankalé; I Thior; I N'Doye; C C Hsieh; S Mboup; P J Kanki
Journal:  J Clin Microbiol       Date:  2000-01       Impact factor: 5.948

9.  Characterization of ompA genotypes by sequence analysis of DNA from all detected cases of Chlamydia trachomatis infections during 1 year of contact tracing in a Swedish County.

Authors:  Maria Lysén; Anders Osterlund; Carl-Johan Rubin; Tina Persson; Ingrid Persson; Björn Herrmann
Journal:  J Clin Microbiol       Date:  2004-04       Impact factor: 5.948

10.  Combination of PCR targeting the VD2 of omp1 and reverse line blot analysis for typing of urogenital Chlamydia trachomatis serovars in cervical scrape specimens.

Authors:  Monica Molano; Chris J L M Meijer; Servaas A Morré; Rene Pol; Adriaan J C van den Brule
Journal:  J Clin Microbiol       Date:  2004-07       Impact factor: 5.948

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