Literature DB >> 8976718

Automatic detection of diabetic retinopathy using an artificial neural network: a screening tool.

G G Gardner1, D Keating, T H Williamson, A T Elliott.   

Abstract

AIMS: To determine if neural networks can detect diabetic features in fundus images and compare the network against an ophthalmologist screening a set of fundus images.
METHODS: 147 diabetic and 32 normal images were captured from a fundus camera, stored on computer, and analysed using a back propagation neural network. The network was trained to recognise features in the retinal image. The effects of digital filtering techniques and different network variables were assessed. 200 diabetic and 101 normal images were then randomised and used to evaluate the network's performance for the detection of diabetic retinopathy against an ophthalmologist.
RESULTS: Detection rates for the recognition of vessels, exudates, and haemorrhages were 91.7%, 93.1%, and 73.8% respectively. When compared with the results of the ophthalmologist, the network achieved a sensitivity of 88.4% and a specificity of 83.5% for the detection of diabetic retinopathy.
CONCLUSIONS: Detection of vessels, exudates, and haemorrhages was possible, with success rates dependent upon preprocessing and the number of images used in training. When compared with the ophthalmologist, the network achieved good accuracy for the detection of diabetic retinopathy. The system could be used as an aid to the screening of diabetic patients for retinopathy.

Entities:  

Mesh:

Year:  1996        PMID: 8976718      PMCID: PMC505667          DOI: 10.1136/bjo.80.11.940

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  21 in total

1.  The application of backpropagation neural networks to problems in pathology and laboratory medicine.

Authors:  M L Astion; P Wilding
Journal:  Arch Pathol Lab Med       Date:  1992-10       Impact factor: 5.534

2.  Artificial neural networks in mammography: application to decision making in the diagnosis of breast cancer.

Authors:  Y Wu; M L Giger; K Doi; C J Vyborny; R A Schmidt; C E Metz
Journal:  Radiology       Date:  1993-04       Impact factor: 11.105

3.  Automatic lung nodule detection using profile matching and back-propagation neural network techniques.

Authors:  S C Lo; M T Freedman; J S Lin; S K Mun
Journal:  J Digit Imaging       Date:  1993-02       Impact factor: 4.056

4.  Cost-effectiveness of alternative methods for diabetic retinopathy screening.

Authors:  N J Wareham
Journal:  Diabetes Care       Date:  1993-05       Impact factor: 19.112

5.  Quantification of diabetic maculopathy by digital imaging of the fundus.

Authors:  R P Phillips; T Spencer; P G Ross; P F Sharp; J V Forrester
Journal:  Eye (Lond)       Date:  1991       Impact factor: 3.775

6.  Non-stereo photographic screening in long-term follow-up for detection of proliferative diabetic retinopathy.

Authors:  H Kalm
Journal:  Acta Ophthalmol (Copenh)       Date:  1992-04

Review 7.  Screening for diabetic retinopathy.

Authors:  D E Singer; D M Nathan; H A Fogel; A P Schachat
Journal:  Ann Intern Med       Date:  1992-04-15       Impact factor: 25.391

8.  Screening for diabetic retinopathy. The wide-angle retinal camera.

Authors:  J A Pugh; J M Jacobson; W A Van Heuven; J A Watters; M R Tuley; D R Lairson; R J Lorimor; A S Kapadia; R Velez
Journal:  Diabetes Care       Date:  1993-06       Impact factor: 19.112

9.  Comparison of diabetic retinopathy detection by clinical examinations and photograph gradings. Barbados (West Indies) Eye Study Group.

Authors:  A P Schachat; L Hyman; M C Leske; A M Connell; C Hiner; N Javornik; J Alexander
Journal:  Arch Ophthalmol       Date:  1993-08

10.  The diagnosis of diabetic retinopathy. Ophthalmoscopy versus fundus photography.

Authors:  V S Lee; R M Kingsley; E T Lee; M Lu; D Russell; N R Asal; R H Bradford; C P Wilkinson
Journal:  Ophthalmology       Date:  1993-10       Impact factor: 12.079

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  46 in total

1.  Automated localisation of the optic disc, fovea, and retinal blood vessels from digital colour fundus images.

Authors:  C Sinthanayothin; J F Boyce; H L Cook; T H Williamson
Journal:  Br J Ophthalmol       Date:  1999-08       Impact factor: 4.638

2.  Automated, real time extraction of fundus images from slit lamp fundus biomicroscope video image sequences.

Authors:  B D Madjarov; J W Berger
Journal:  Br J Ophthalmol       Date:  2000-06       Impact factor: 4.638

3.  Effect of digital image compression on screening for diabetic retinopathy.

Authors:  R S Newsom; A Clover; M T Costen; J Sadler; J Newton; A J Luff; C R Canning
Journal:  Br J Ophthalmol       Date:  2001-07       Impact factor: 4.638

4.  Automated identification of diabetic retinal exudates in digital colour images.

Authors:  A Osareh; M Mirmehdi; B Thomas; R Markham
Journal:  Br J Ophthalmol       Date:  2003-10       Impact factor: 4.638

Review 5.  Retinal imaging and image analysis.

Authors:  Michael D Abràmoff; Mona K Garvin; Milan Sonka
Journal:  IEEE Rev Biomed Eng       Date:  2010

6.  Validating retinal fundus image analysis algorithms: issues and a proposal.

Authors:  Emanuele Trucco; Alfredo Ruggeri; Thomas Karnowski; Luca Giancardo; Edward Chaum; Jean Pierre Hubschman; Bashir Al-Diri; Carol Y Cheung; Damon Wong; Michael Abràmoff; Gilbert Lim; Dinesh Kumar; Philippe Burlina; Neil M Bressler; Herbert F Jelinek; Fabrice Meriaudeau; Gwénolé Quellec; Tom Macgillivray; Bal Dhillon
Journal:  Invest Ophthalmol Vis Sci       Date:  2013-05-01       Impact factor: 4.799

7.  ELHnet: a convolutional neural network for classifying cochlear endolymphatic hydrops imaged with optical coherence tomography.

Authors:  George S Liu; Michael H Zhu; Jinkyung Kim; Patrick Raphael; Brian E Applegate; John S Oghalai
Journal:  Biomed Opt Express       Date:  2017-09-20       Impact factor: 3.732

8.  Investigations of severity level measurements for diabetic macular oedema using machine learning algorithms.

Authors:  S Murugeswari; R Sukanesh
Journal:  Ir J Med Sci       Date:  2017-05-15       Impact factor: 1.568

9.  A novel diagnostic method for pituitary adenoma based on magnetic resonance imaging using a convolutional neural network.

Authors:  Yu Qian; Yue Qiu; Cheng-Cheng Li; Zhong-Yuan Wang; Bo-Wen Cao; Hong-Xin Huang; Yi-Hong Ni; Lu-Lu Chen; Jin-Yu Sun
Journal:  Pituitary       Date:  2020-06       Impact factor: 4.107

10.  A system for computerised retinal haemorrhage analysis.

Authors:  Tariq Aslam; Paul Chua; Matthew Richardson; Praveen Patel; Mohammed Musadiq
Journal:  BMC Res Notes       Date:  2009-09-28
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