N J Christmas1, W E Smiddy. 1. Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami School of Medicine, FL 33101, USA.
Abstract
BACKGROUND AND OBJECTIVE: To investigate the efficacy of pars plana vitrectomy and oral fluconazole without injection of intravitreal antimycotic agents in the treatment of vitritis resulting from Candida endophthalmitis. PATIENTS AND METHODS: Six eyes of five patients with suspected Candida endophthalmitis were treated with pars plana vitrectomy and systemic fluconazole for at least 3 weeks. Patients were observed postoperatively for at least 4 months. RESULTS: Clinical signs of infection cleared and visual acuity improved postoperatively in all six cases. One recurrent case was attributed to a retained indwelling venous catheter. CONCLUSIONS: Treatment of advanced endogenous Candida endophthalmitis with vitrectomy and systemic fluconazole offers an effective alternative to management with intravitreal amphotericin B in selected cases.
BACKGROUND AND OBJECTIVE: To investigate the efficacy of pars plana vitrectomy and oral fluconazole without injection of intravitreal antimycotic agents in the treatment of vitritis resulting from Candida endophthalmitis. PATIENTS AND METHODS: Six eyes of five patients with suspected Candida endophthalmitis were treated with pars plana vitrectomy and systemic fluconazole for at least 3 weeks. Patients were observed postoperatively for at least 4 months. RESULTS: Clinical signs of infection cleared and visual acuity improved postoperatively in all six cases. One recurrent case was attributed to a retained indwelling venous catheter. CONCLUSIONS: Treatment of advanced endogenous Candida endophthalmitis with vitrectomy and systemic fluconazole offers an effective alternative to management with intravitreal amphotericin B in selected cases.
Authors: Hua Gao; Mark Pennesi; Kekul Shah; Xiaoxi Qiao; Seenu M Hariprasad; William F Mieler; Samuel M Wu; Eric R Holz Journal: Trans Am Ophthalmol Soc Date: 2003
Authors: Antonio Vena; Patricia Muñoz; Belen Padilla; Maricela Valerio; Maria Isabel Sanchez; Mireia Puig-Asensio; Jesus Fortun; Mario Fernandez-Ruiz; Paloma Merino; Juan Emilio Losa; Ana Loza; Rosa Ana Rivas; Emilio Bouza Journal: PLoS One Date: 2017-10-24 Impact factor: 3.240