Literature DB >> 8973716

Localization of Cu/Zn-SOD and Mn-SOD in the rat cochlea.

K E Rarey1, X Yao.   

Abstract

Distributions of the copper/zinc-superoxide dismutase (Cu/Zn-SOD) and the manganese superoxide dismutase (Mn-SOD) in the rat cochlea were studied by immunohistochemistry with specific polyclonal antibodies to Mn-SOD and Cu/Zn-SOD. Coexpression of Mn-SOD and Cu/Zn-SOD was observed in the cochlear tissues with differing immunoactivity intensities. The presence of Cu/Zn- and Mn-SOD implies the existence of a defense system against free oxygen radical (FOR) injury in cochlear tissues.

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Year:  1996        PMID： 8973716     DOI： 10.3109/00016489609137935

Source DB:  PubMed          Journal:  Acta Otolaryngol        ISSN： 0001-6489            Impact factor:   1.494


  6 in total

1.  Chronic reduction of endocochlear potential reduces auditory nerve activity: further confirmation of an animal model of metabolic presbyacusis.

Authors:  Hainan Lang; Vinu Jyothi; Nancy M Smythe; Judy R Dubno; Bradley A Schulte; Richard A Schmiedt
Journal:  J Assoc Res Otolaryngol       Date:  2010-04-06

2.  The spatio-temporal expression pattern of cytoplasmic Cu/Zn superoxide dismutase (SOD1) mRNA during mouse embryogenesis.

Authors:  Jung-Min Yon; In-Jeoung Baek; Se-Ra Lee; Yan Jin; Mi-Ra Kim; Sang-Seop Nahm; Jong-Soo Kim; Byeongwoo Ahn; Beom Jun Lee; Young Won Yun; Sang-Yoon Nam
Journal:  J Mol Histol       Date:  2007-09-05       Impact factor: 2.611

3.  Is Hypozincemia Related to Tinnitus?: A Population Study Using Data From the Korea National Health and Nutrition Examination Survey.

Authors:  Hyung Jin Jun; Sohea Ok; Richard Tyler; Soon Young Hwang; Sungwon Chae
Journal:  Clin Exp Otorhinolaryngol       Date:  2015-11-10       Impact factor: 3.372

4.  Cu/Zn superoxide dismutase and age-related hearing loss.

Authors:  Elizabeth M Keithley; Cecilia Canto; Qing Yin Zheng; Xiaobo Wang; Nathan Fischel-Ghodsian; Kenneth R Johnson
Journal:  Hear Res       Date:  2005-08-01       Impact factor: 3.208

5.  Attenuation of progressive hearing loss in DBA/2J mice by reagents that affect epigenetic modifications is associated with up-regulation of the zinc importer Zip4.

Authors:  Hideki Mutai; Fuyuki Miya; Masato Fujii; Tatsuhiko Tsunoda; Tatsuo Matsunaga
Journal:  PLoS One       Date:  2015-04-14       Impact factor: 3.240

6.  Validation of Reference Genes for RT-qPCR Analysis in Noise-Induced Hearing Loss: A Study in Wistar Rat.

Authors:  Pedro Melgar-Rojas; Juan Carlos Alvarado; Verónica Fuentes-Santamaría; María Cruz Gabaldón-Ull; José M Juiz
Journal:  PLoS One       Date:  2015-09-14       Impact factor: 3.240
  6 in total

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