Literature DB >> 8973355

Genomic organization of mouse Dishevelled genes.

Y Yang1, N Lijam, D J Sussman, M Tsang.   

Abstract

We report the isolation and characterization of two new genomic loci corresponding to the mouse Dishevelled (Dvl) genes Dvl2 and Dvl3. The Dvl genes are homologs of the Drosophila dsh segment polarity gene, and are involved in the Wnt/wingless signal transduction pathway. Dvl2 and Dvl3 genomic clones were isolated from a mouse 129 strain gamma FIXII genomic library and have identical exon/intron organization to Dvl1. All three Dishevelled genes span 15 exons and 14 introns and have a number of conserved splice junction sites.

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Year:  1996        PMID： 8973355     DOI： 10.1016/s0378-1119(96)00430-1

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  6 in total

1.  Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis.

Authors:  U Rothbächer; M N Laurent; M A Deardorff; P S Klein; K W Cho; S E Fraser
Journal:  EMBO J       Date:  2000-03-01       Impact factor: 11.598

Review 2.  The way Wnt works: components and mechanism.

Authors:  Kenyi Saito-Diaz; Tony W Chen; Xiaoxi Wang; Curtis A Thorne; Heather A Wallace; Andrea Page-McCaw; Ethan Lee
Journal:  Growth Factors       Date:  2012-12-21       Impact factor: 2.511

3.  Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin.

Authors:  José M González-Sancho; Keith R Brennan; Leslie A Castelo-Soccio; Anthony M C Brown
Journal:  Mol Cell Biol       Date:  2004-06       Impact factor: 4.272

4.  Dishevelled-1 regulates microtubule stability: a new function mediated by glycogen synthase kinase-3beta.

Authors:  O Krylova; M J Messenger; P C Salinas
Journal:  J Cell Biol       Date:  2000-10-02       Impact factor: 10.539

5.  Whole genome variant association across 100 dogs identifies a frame shift mutation in DISHEVELLED 2 which contributes to Robinow-like syndrome in Bulldogs and related screw tail dog breeds.

Authors:  Tamer A Mansour; Katherine Lucot; Sara E Konopelski; Peter J Dickinson; Beverly K Sturges; Karen L Vernau; Shannon Choi; Joshua A Stern; Sara M Thomasy; Sophie Döring; Frank J M Verstraete; Eric G Johnson; Daniel York; Robert B Rebhun; Hsin-Yi Henry Ho; C Titus Brown; Danika L Bannasch
Journal:  PLoS Genet       Date:  2018-12-06       Impact factor: 5.917

6.  Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development.

Authors:  S Leah Etheridge; Saugata Ray; Shuangding Li; Natasha S Hamblet; Nardos Lijam; Michael Tsang; Joy Greer; Natalie Kardos; Jianbo Wang; Daniel J Sussman; Ping Chen; Anthony Wynshaw-Boris
Journal:  PLoS Genet       Date:  2008-11-14       Impact factor: 5.917
  6 in total

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