Literature DB >> 897207

A possible role of prostaglandins in guinea-pig isolated ileum contractions to serotonin.

J P Famaey, J Fontaine, I Seaman, J Reuse.   

Abstract

Nine non-steroidal antiinflammatory drugs have been tested for their effect on contractions to serotonin of the guinea-pig isolated ileum. They exert a potent inhibition which is totally reversible by washing out the drugs. It is also well reversed by the addition of small amounts of PGE1 to the bath. It is concluded that prostaglandins exert a role in these contractions to serotonin which is probably specific as well as non specific.

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Year:  1977        PMID: 897207     DOI: 10.1016/0090-6980(77)90160-5

Source DB:  PubMed          Journal:  Prostaglandins        ISSN: 0090-6980


  2 in total

1.  The effects of antiinflammatory steroids on the response of the guinea-pig isolated ileum to acetylcholine, histamine, nicotine, 5-hydroxytryptamine and electrical stimulation.

Authors:  J P Famaey; J Fontaine; I Seaman; J Reuse
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1979-11       Impact factor: 3.000

Review 2.  Prostaglandins and serotonin: nonpeptide diarrheogenic hormones.

Authors:  B M Jaffe
Journal:  World J Surg       Date:  1979-09-20       Impact factor: 3.352

  2 in total

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