Effect of bright light exposure on muscle sympathetic nerve activity in human.

To evaluate the effect of bright light on the sympathetic nervous system in human, muscle sympathetic nerve activity (MSNA) was recorded from the peroneal nerve in five healthy subjects. Each subject was exposed to bright light of 5000 lx for 20 min. After the bright light exposure, MSNA became significantly enhanced. The heart rate increased transiently only during the bright light exposure. The blood pressure did not change significantly during and after the bright light exposure. The result is the first direct evidence showing that bright light modulates the activity of the sympathetic nervous system in normal human.