Literature DB >> 8968145

Myocardial revascularization procedures on multisegment diseased left anterior descending artery: endarterectomy or multiple sequential anastomoses (jumping)?

F Alamanni1, A Parolari, M Agrifoglio, N Valerio, M Zanobini, A Repossini, V Arena, A Sala, C Antona, P Biglioli.   

Abstract

Complete revascularization is the primary goal in coronary surgery because of its superior long term results. However, in some patients the extent of the coronary artery disease is such that the usual coronary bypass technique may not allow to perform a complete myocardial surgical revascularization and, consequently, a satisfactory myocardial perfusion: so complementary revascularization techniques may become mandatory, especially when the diseased vessel is LAD or its branches. As a consequence, alternative procedures should be undertaken: coronary endarterectomy (EA) and multiple sequential anastomoses on a single vessel (jump), which guidelines are actually somehow controversial. Between January, 1989, and May, 1992, 53 patients underwent a myocardial revascularization procedure on LAD system unsuitable for single distal bypass; of them 35 (66%) underwent coronary endarterectomy, while in 18 (34%) multiple sequential anastomoses (jumping) were performed on the same vessel. About preoperative variables, average NYHA class (2.7 jump vs 2.1 EA group, p < 0.05), the history of more than 1 myocardial infarction (22.2% jump vs 2.9% EA, p < 0.04) and the presence of preoperative nitrates e.v (33.3% vs 8.6%, p < 0.04) were statistically higher in the jump group, suggesting a more unstable clinical status, while other clinical echocardiographic and catheterization features were not statistically different. For what operative and postoperative features are concerned, the number of anastomoses performed was statistically higher in the jump group, as exasperated (3.8 vs 2.7, p < 0.002) while perfusion (138 vs 141 min) and crossclamp time (103 vs 106 min) were similar. Furthermore we found a statistically lower incidence of perioperative myocardial infarction (0% jump is 22.8% EA group, p < 0.04); the postperfusion inotropic drugs requirement (22.2% vs 37.1%), the need of an intraaortic counterpulsation (0% vs 2.9%) and the in-hospital mortality (0% vs 5.7%) were lower in the jumping group too, also if they didn't reach statistical significance. Our experience suggest, also with the limits imposed by a retrospective case review and by a low number of cases reported, that myocardial revascularization of a multisegment diseased LAD system may be safely performed with the jumping technique with a low incidence of postoperative complications: it should be the first choice technique when conventional revascularization procedures are not enough to achieve complete myocardial revascularization. We advocate the use of EA technique only in that cases characterized by a diffuse atherosclerotic core and a well delimited plane of dissection, associated to a very poor runoff, which really excludes any chance to multiple anastomoses.

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Year:  1996        PMID: 8968145

Source DB:  PubMed          Journal:  Minerva Cardioangiol        ISSN: 0026-4725            Impact factor:   1.347


  6 in total

1.  Sequential left internal mammary artery usage for complex left anterior descending coronary artery revascularization.

Authors:  Ufuk Aydin; Yusuf Ata
Journal:  Int J Clin Exp Med       Date:  2014-04-15

2.  Alternative option in patients with multisegmental left anterior descending coronary artery disease for providing complete myocardial revascularization.

Authors:  Arif Gucu; Tuğrul Goncu; Senol Yavuz; Ozlem Arican Ozluk; Cuneyt Eris; Tamer Turk; Ahmet Ozyazıcıoglu; Hakan Vural
Journal:  Int J Clin Exp Med       Date:  2014-01-15

3.  Tandem pedicled internal thoracic artery conduit for sequential grafting of multiple left anterior descending coronary artery lesions.

Authors:  Dusko Nezic; Aleksandar Knezevic; Predrag Milojevic; Miomir Jovic; Dragan Sagic; Bosko Djukanovic
Journal:  Tex Heart Inst J       Date:  2006

4.  Long term follow up results of sequential left internal thoracic artery grafts on severe left anterior descending artery disease.

Authors:  Murat Mert; Gurkan Cetin; Cenk Eray Yildiz; Murat Ugurlucan; Ilker Murat Caglar; Ahmet Ozkara; Atif Akcevin; Cihat Bakay
Journal:  J Cardiothorac Surg       Date:  2010-10-19       Impact factor: 1.637

5.  Surgical management of diffusely diseased coronary arteries.

Authors:  Gutti Ramasubrahmanyam; Karthik Panchanatheeswaran; Tej Kumar Varma Kalangi; Goli Nagasaina Rao
Journal:  Indian J Thorac Cardiovasc Surg       Date:  2019-01-07

6.  Short- and Long-Term Patient Outcomes From Combined Coronary Endarterectomy and Coronary Artery Bypass Grafting: A Meta-Analysis of 63,730 Patients (PRISMA).

Authors:  Jiayang Wang; Chengxiong Gu; Wenyuan Yu; Mingxin Gao; Yang Yu
Journal:  Medicine (Baltimore)       Date:  2015-10       Impact factor: 1.817

  6 in total

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