Literature DB >> 8967759

Bell's Palsy-associated blepharospasm relieved by aiding eyelid closure.

J C Chuke1, R S Baker, J D Porter.   

Abstract

The efficacy of the blink reflex is maintained by adaptive control mechanisms. We describe a 39-year-old woman with the rare complication of blepharospasm-like symptoms appearing contralateral to an eyelid weakened by facial nerve palsy. The hyperexcitable blink reflex may be a maladaptive consequence of adaptive systems but was not accompanied by an expected increase in main sequence slope. Eyelid spasms were eliminated by the implantation of a gold weight to assist closure of the paretic eyelid. We suggest that aiding closure of the weak eyelid in this case caused a reduction in blink system excitability via the same compensatory mechanisms that initially produced the eyelid spasm. Data also suggest that blink-adaptive systems act via changes in reflex excitability and/or main sequence relationships, and that these may be regulated either synergistically or independent of one another.

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Year:  1996        PMID: 8967759     DOI: 10.1002/ana.410390217

Source DB:  PubMed          Journal:  Ann Neurol        ISSN: 0364-5134            Impact factor:   10.422


  4 in total

Review 1.  Neurophysiology of dystonia: The role of inhibition.

Authors:  Mark Hallett
Journal:  Neurobiol Dis       Date:  2010-09-15       Impact factor: 5.996

2.  Impact of early eyelid weight placement on the development of synkinesis and recovery in patients with idiopathic facial paralysis.

Authors:  Keon M Parsa; Caroline Rieger; Dara Khatib; Jennifer R White; Jodi Barth; Chad C Zatezalo; Michael J Reilly
Journal:  World J Otorhinolaryngol Head Neck Surg       Date:  2020-06-12

3.  Animal models for investigating benign essential blepharospasm.

Authors:  Craig Evinger
Journal:  Curr Neuropharmacol       Date:  2013-01       Impact factor: 7.363

Review 4.  Blepharospasm: Update on Epidemiology, Clinical Aspects, and Pathophysiology.

Authors:  Josep Valls-Sole; Giovanni Defazio
Journal:  Front Neurol       Date:  2016-03-31       Impact factor: 4.003

  4 in total

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