Literature DB >> 8963402

Hemolytic anemia provoked by recombinant alpha-interferon.

K Takase1, T Nakano, M Hamada, K Shiraki, Y Oohashi, T Kihira, Y Tameda.   

Abstract

A 30-year-old female with chronic hepatitis C treated with recombinant alpha-interferon developed serious hemolytic anemia after receiving 10 million units a day for 4 weeks. The results of Coombs' tests were negative before and after interferon therapy. The hemolytic anemia gradually improved after the withdrawal of recombinant alpha-interferon and the administration of methyl-prednisolone. The clinical course suggested that the recombinant alpha-interferon had provoked the hemolytic anemia.

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Year:  1995        PMID： 8963402     DOI： 10.1007/bf02349651

Source DB:  PubMed          Journal:  J Gastroenterol        ISSN： 0944-1174            Impact factor:   7.527


  9 in total

1.  Treatment of chronic non-A,non-B hepatitis with recombinant human alpha interferon. A preliminary report.

Authors:  J H Hoofnagle; K D Mullen; D B Jones; V Rustgi; A Di Bisceglie; M Peters; J G Waggoner; Y Park; E A Jones
Journal:  N Engl J Med       Date:  1986-12-18       Impact factor: 91.245

2.  Hemolytic anemia secondary to interferon treatment for chronic B hepatitis.

Authors:  G Fornaciari; C Bassi; M Beltrami; E Castagnetti; S Maccari; A C Plancher
Journal:  J Clin Gastroenterol       Date:  1991-10       Impact factor: 3.062

Review 3.  Side effects of alpha interferon.

Authors:  P F Renault; J H Hoofnagle
Journal:  Semin Liver Dis       Date:  1989-11       Impact factor: 6.115

4.  Autoimmunity after alpha-interferon therapy for malignant carcinoid tumors.

Authors:  L E Rönnblom; G V Alm; K E Oberg
Journal:  Ann Intern Med       Date:  1991-08-01       Impact factor: 25.391

5.  Alpha-interferon and immune hemolytic anemia.

Authors:  L P Akard; R Hoffman; L Elias; J H Saiers
Journal:  Ann Intern Med       Date:  1986-08       Impact factor: 25.391

6.  Primary hypothyroidism associated with interferon therapy of breast cancer.

Authors:  I S Fentiman; B S Thomas; F R Balkwill; R D Rubens; J L Hayward
Journal:  Lancet       Date:  1985-05-18       Impact factor: 79.321

7.  Interferon-induced parotitis and epididymitis.

Authors:  P C Bevan
Journal:  Lancet       Date:  1985-09-07       Impact factor: 79.321

8.  Immune thrombocytopenia following alpha-interferon therapy in patients with cancer.

Authors:  P McLaughlin; M Talpaz; J R Quesada; A Saleem; B Barlogie; J U Gutterman
Journal:  JAMA       Date:  1985-09-13       Impact factor: 56.272

9.  Effects of interferon-alpha on the expression of a lupus idiotype in normal humans.

Authors:  A Schattner; D Duggan; Y Naparstek; R S Schwartz
Journal:  Clin Immunol Immunopathol       Date:  1986-03
  9 in total

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