| Literature DB >> 8962879 |
Abstract
Bacillus cereus hemolysin III activity was tested in crude extracts, from Escherichia coli carrying the hly-III gene. It was concluded that hemolysin III is a pore-forming hemolysin with functional pore diameter of about 3-3.5 nm. Hemolysis occurs in at least three steps: (i) the temperature-dependent binding of the Hly-III monomers to the erythrocyte membrane; (ii) the temperature-dependent formation of the transmembrane oligomeric pore; (iii) the temperature-independent erythrocyte lysis.Entities:
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Year: 1996 PMID: 8962879 DOI: 10.1016/s0005-2736(96)00168-x
Source DB: PubMed Journal: Biochim Biophys Acta ISSN: 0006-3002