Literature DB >> 8962191

A novel mechanism of action of the immunomodulatory drug, leflunomide: augmentation of the immunosuppressive cytokine, TGF-beta 1, and suppression of the immunostimulatory cytokine, IL-2.

W W Cao1, P N Kao, Y Aoki, J C Xu, R A Shorthouse, R E Morris.   

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Year:  1996        PMID: 8962191

Source DB:  PubMed          Journal:  Transplant Proc        ISSN: 0041-1345            Impact factor:   1.066


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  15 in total

Review 1.  Leflunomide: a review of its use in active rheumatoid arthritis.

Authors:  A Prakash; B Jarvis
Journal:  Drugs       Date:  1999-12       Impact factor: 9.546

2.  Leflunomide: an unlikely trigger and mechanistically a beneficial drug for alopecia areata.

Authors:  Kabir Sardana; Aastha Gupta; Pulin Kumar Gupta
Journal:  Clin Rheumatol       Date:  2019-07-23       Impact factor: 2.980

Review 3.  A review of immunologic diseases of the dog.

Authors:  N C Pedersen
Journal:  Vet Immunol Immunopathol       Date:  1999-08-02       Impact factor: 2.046

Review 4.  Leflunomide: mode of action in the treatment of rheumatoid arthritis.

Authors:  F C Breedveld; J M Dayer
Journal:  Ann Rheum Dis       Date:  2000-11       Impact factor: 19.103

5.  The effect of various disease-modifying anti-rheumatic drugs on the suppressive function of CD4⁺CD25⁺ regulatory T cells.

Authors:  Ji Seon Oh; Yong-Gil Kim; Seung Geun Lee; Min Wook So; Seung Won Choi; Chang-Keun Lee; Bin Yoo
Journal:  Rheumatol Int       Date:  2012-03-27       Impact factor: 2.631

6.  Leflunomide: new antirheumatic drug. Effect on pregnancy outcomes.

Authors:  E Kozer; M E Moretti; G Koren
Journal:  Can Fam Physician       Date:  2001-04       Impact factor: 3.275

7.  Teriflunomide Modulates Vascular Permeability and Microglial Activation after Experimental Traumatic Brain Injury.

Authors:  Karthik S Prabhakara; Daniel J Kota; Gregory H Jones; Amit K Srivastava; Charles S Cox; Scott D Olson
Journal:  Mol Ther       Date:  2018-07-05       Impact factor: 11.454

8.  Pulmonary abscess due to leflunomide use in rheumatoid arthritis: a case report.

Authors:  H Ulusoy; A Bilgici; O Kuru; C Celenk
Journal:  Rheumatol Int       Date:  2004-08-21       Impact factor: 2.631

Review 9.  Benefit-risk assessment of leflunomide: an appraisal of leflunomide in rheumatoid arthritis 10 years after licensing.

Authors:  Nicola Alcorn; Sarah Saunders; Rajan Madhok
Journal:  Drug Saf       Date:  2009       Impact factor: 5.606

10.  Review of teriflunomide and its potential in the treatment of multiple sclerosis.

Authors:  Clemens Warnke; Gerd Meyer zu Hörste; Hans-Peter Hartung; Olaf Stüve; Bernd C Kieseier
Journal:  Neuropsychiatr Dis Treat       Date:  2009-06-10       Impact factor: 2.570

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