Literature DB >> 8960544

Potent, selective, orally active 3-oxo-1,4-benzodiazepine GPIIb/IIIa integrin antagonists.

J M Samanen1, F E Ali, L S Barton, W E Bondinell, J L Burgess, J F Callahan, R R Calvo, W Chen, L Chen, K Erhard, G Feuerstein, R Heys, S M Hwang, D R Jakas, R M Keenan, T W Ku, C Kwon, C P Lee, W H Miller, K A Newlander, A Nichols, M Parker, C E Peishoff, G Rhodes, S Ross, A Shu, R Simpson, D Takata, T O Yellin, I Uzsinskas, J W Venslavsky, C K Yuan, W F Huffman.   

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Year:  1996        PMID: 8960544     DOI: 10.1021/jm960558a

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  6 in total

Review 1.  Mechanisms of tumor angiogenesis and therapeutic implications: angiogenesis inhibitors.

Authors:  H Malonne; I Langer; R Kiss; G Atassi
Journal:  Clin Exp Metastasis       Date:  1999-02       Impact factor: 5.150

Review 2.  The significance of G protein-coupled receptor crystallography for drug discovery.

Authors:  John A Salon; David T Lodowski; Krzysztof Palczewski
Journal:  Pharmacol Rev       Date:  2011-12       Impact factor: 25.468

3.  General one-pot, two-step protocol accessing a range of novel polycyclic heterocycles with high skeletal diversity.

Authors:  Zhigang Xu; Muhammad Ayaz; Alexandra A Cappelli; Christopher Hulme
Journal:  ACS Comb Sci       Date:  2012-07-12       Impact factor: 3.784

4.  Synthesis of Tetrazolo-Fused Benzodiazepines and Benzodiazepinones by a Two-Step Protocol Using an Ugi-Azide Reaction for Initial Diversity Generation.

Authors:  Steven Gunawan; Muhammad Ayaz; Fabio De Moliner; Brendan Frett; Christine Kaiser; Nina Patrick; Zhigang Xu; Christopher Hulme
Journal:  Tetrahedron       Date:  2012-04-26       Impact factor: 2.457

Review 5.  Emerging molecular diversity from the intra-molecular Ugi reaction: iterative efficiency in medicinal chemistry.

Authors:  Christopher Hulme; Justin Dietrich
Journal:  Mol Divers       Date:  2009-02-11       Impact factor: 3.364

6.  Bitistatin-functionalized fluorescent nanodiamond particles specifically bind to purified human platelet integrin receptor αIIbβ3 and activated platelets.

Authors:  Cezary Marcinkiewicz; Jonathan A Gerstenhaber; Mark Sternberg; Peter I Lelkes; Giora Feuerstein
Journal:  Int J Nanomedicine       Date:  2017-05-15
  6 in total

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