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Literature DB >> 8959405

Polycyclic aromatic hydrocarbons and cancer in man.

Abstract

Various substances and industrial processes, surrogates of exposure to polycyclic aromatic hydrocarbons (PAHs), are currently classified as human carcinogens. This paper reviews recent epidemiological studies reporting direct evidence of the carcinogenic effects of PAHs in occupationally exposed subjects. Risks of lung and bladder cancer were dose dependent when PAHs were measured quantitatively and truly nonexposed groups were chosen for comparison. These new findings suggest that the current threshold limit value of 0.2 mg/m3 of benzene soluble matter (which indicates PAH exposure) is unacceptable because, after 40 years of exposure, it involves a relative risk of 1.2-1.4 for lung cancer and 2.2 for bladder cancer.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1996 PMID： 8959405 PMCID： PMC1469515 DOI： 10.1289/ehp.961041166

Source DB: PubMed Journal: Environ Health Perspect ISSN： 0091-6765 Impact factor: 9.031

24 in total

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68 in total

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Authors: Behnoush Abedi-Ardekani; Farin Kamangar; Stephen M Hewitt; Pierre Hainaut; Masoud Sotoudeh; Christian C Abnet; Philip R Taylor; Paolo Boffetta; Reza Malekzadeh; Sanford M Dawsey
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Journal: J Microbiol Date: 2018-10-24 Impact factor: 3.422