Literature DB >> 895715

Cytoplasmic and mitochondrial protein synthesis in the "petite-negative" yeast Kluyveromyces lactis. Cytoplasmic inheritance of resistance to tetracycline.

A M Guerrini, B Luciano, F Cavaliere.   

Abstract

The growth of two strains of the "petite-negative" yeast Kluyveromyces lactis is inhibited by Tetracycline in different ways under the same culture conditions. Tetracycline resistant mutants of one strain have been isolated which can tolerate doses as high as 3000 microgram/ml of antibiotic. The segregation pattern of this character obtained by random spore analysis of the ascospores derived from the cross of the two strains strongly suggests that the resistance to tetracycline is under mitochondrial control.

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Year:  1977        PMID: 895715     DOI: 10.1007/bf00330834

Source DB:  PubMed          Journal:  Mol Gen Genet        ISSN: 0026-8925


  9 in total

1.  Studies on a temperature sensitive nuclear petite mutant of Saccharomyces cerevisiae: phenotypic reversibility of the mitochondrial functions.

Authors:  A M Guerrini; M A Pedrini; F Cavaliere; E Gionti
Journal:  Mol Gen Genet       Date:  1975-09-29

2.  Chromosomal and extrachromosomal inheritance of erythromycin-resistance in the "petite-negative" yeast Kluyveromyces lactis.

Authors:  L Del Giudice; A Brunner
Journal:  Mol Gen Genet       Date:  1977-04-29

3.  Synchronous mating in yeast.

Authors:  E P Sena; D N Radin; S Fogel
Journal:  Proc Natl Acad Sci U S A       Date:  1973-05       Impact factor: 11.205

4.  Genetic analysis of mitochondrial resistance to tetracycline in Saccharomyces cerevisiae.

Authors:  A R Hughes; D Wilkie
Journal:  Heredity (Edinb)       Date:  1972-02       Impact factor: 3.821

5.  The intracellular site of formation of the mitochondrial protein synthetic system.

Authors:  P J Davey; R Yu; A W Linnane
Journal:  Biochem Biophys Res Commun       Date:  1969-07-07       Impact factor: 3.575

6.  Chloramphenicol inhibition of the formation of particulate mitochondrial enzymes of Saccharomyces cerevisiae.

Authors:  M Huang; D R Biggs; G D Clark-Walker; A W Linnane
Journal:  Biochim Biophys Acta       Date:  1966-02-21

7.  In vivo differentiation of yeast cytoplasmic and mitochondrial protein synthesis with antibiotics.

Authors:  G D Clark-Walker; A W Linnane
Journal:  Biochem Biophys Res Commun       Date:  1966-10-05       Impact factor: 3.575

8.  Inhibition of respiratory enzyme synthesis in yeast by chloramphenicol: relationship between chloramphenicol tolerance and resistance to other antibacterial antibiotics.

Authors:  D Wilkie; G Saunders; A W Linnane
Journal:  Genet Res       Date:  1967-10       Impact factor: 1.588

9.  Dependence of cytoplasmic on mitochondrial protein synthesis in K. Lactis CBS 2360. I. Biochemical analysis.

Authors:  E Zennaro; C Falcone; L Frontali; P P Puglisi
Journal:  Mol Gen Genet       Date:  1977-01-18
  9 in total

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