Literature DB >> 8955534

Expression of nicotinic acetylcholine receptor mRNA in the adult rat peripheral vestibular system.

H Hiel1, A B Elgoyhen, D G Drescher, B J Morley.   

Abstract

The mRNA expression of the neuronal nicotinic acetylcholine receptor subunits was determined in adult rat vestibular end-organs and in Scarpa's ganglion (SCG) by in situ hybridization with [35S] riboprobes. Neurons in the SCG expressed the alpha 4-7 and beta 2-3 mRNAs, but not alpha 3 or beta 4 mRNAs. Not all SCG neurons expressed every mRNA found in SCG. The alpha 6 and beta 2-3 riboprobes labeled all neurons, but alpha 4, alpha 5, and alpha 7 mRNAs were selectively expressed in one or more subpopulations of SCG neurons. Vestibular sensory hair cells, in contrast, expressed only alpha 9 mRNA.

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Year:  1996        PMID: 8955534     DOI: 10.1016/s0006-8993(96)01046-3

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  28 in total

1.  Mechanisms of efferent-mediated responses in the turtle posterior crista.

Authors:  Joseph C Holt; Anna Lysakowski; Jay M Goldberg
Journal:  J Neurosci       Date:  2006-12-20       Impact factor: 6.167

2.  Efferent Inputs Are Required for Normal Function of Vestibular Nerve Afferents.

Authors:  Vishal Raghu; Richard Salvi; Soroush G Sadeghi
Journal:  J Neurosci       Date:  2019-07-08       Impact factor: 6.167

3.  Efferent synaptic transmission at the vestibular type II hair cell synapse.

Authors:  Zhou Yu; J Michael McIntosh; Soroush G Sadeghi; Elisabeth Glowatzki
Journal:  J Neurophysiol       Date:  2020-07-01       Impact factor: 2.714

4.  Visualization of alpha9 acetylcholine receptor expression in hair cells of transgenic mice containing a modified bacterial artificial chromosome.

Authors:  J Zuo; J Treadaway; T W Buckner; B Fritzsch
Journal:  Proc Natl Acad Sci U S A       Date:  1999-11-23       Impact factor: 11.205

5.  Muscarinic acetylcholine receptor subtype expression in type vestibular hair cells of guinea pigs.

Authors:  Qi Yao; Huamao Cheng; Changkai Guo; Tao Zhou; Xiang Huang; Weijia Kong
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2011-10-25

6.  Alpha-9 nicotinic acetylcholine receptor immunoreactivity in the rodent vestibular labyrinth.

Authors:  Anne E Luebke; Paul D Maroni; Scott M Guth; Anna Lysakowski
Journal:  J Comp Neurol       Date:  2005-11-21       Impact factor: 3.215

Review 7.  A review of efferent cholinergic synaptic transmission in the vestibular periphery and its functional implications.

Authors:  L A Poppi; J C Holt; R Lim; A M Brichta
Journal:  J Neurophysiol       Date:  2019-12-04       Impact factor: 2.714

8.  BK channels mediate cholinergic inhibition of high frequency cochlear hair cells.

Authors:  Eric Wersinger; Will J McLean; Paul A Fuchs; Sonja J Pyott
Journal:  PLoS One       Date:  2010-11-04       Impact factor: 3.240

9.  Cholinergic Modulation of Membrane Properties of Calyx Terminals in the Vestibular Periphery.

Authors:  Yugandhar Ramakrishna; Marco Manca; Elisabeth Glowatzki; Soroush G Sadeghi
Journal:  Neuroscience       Date:  2020-11-13       Impact factor: 3.590

10.  Constitutive expression of the alpha10 nicotinic acetylcholine receptor subunit fails to maintain cholinergic responses in inner hair cells after the onset of hearing.

Authors:  Julián Taranda; Jimena A Ballestero; Hakim Hiel; Flavio S J de Souza; Carolina Wedemeyer; M Eugenia Gómez-Casati; Marcela Lipovsek; Douglas E Vetter; Paul A Fuchs; Eleonora Katz; A Belén Elgoyhen
Journal:  J Assoc Res Otolaryngol       Date:  2009-05-19
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