Literature DB >> 8955529

Enteric neurons express Steel factor-lacZ transgene in the murine gastrointestinal tract.

S Torihashi1, H Yoshida, S Nishikawa, T Kunisada, K M Sanders.   

Abstract

The cells that express Steel factor (SLF) in the gastrointestinal (GI) tract were studied using SLF-lacZ transgenic mice. Expression, detected by beta-galactosidase histochemistry, was evident in cells between the circular and longitudinal muscle layers in the GI tract. Double staining with antibodies specific for the neural markers, PGP 9.5, MAP2 and c-Ret, showed that SLF-lacZ positive cells were enteric neurons. Enteroglia did not express SLF-lacZ. The distribution of expressing cells was complimentary to the expression of c-Kit in myenteric interstitial cells.

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Year:  1996        PMID: 8955529     DOI: 10.1016/s0006-8993(96)00935-3

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  11 in total

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Review 8.  Development of interstitial cells of Cajal in the human digestive tract as the result of reciprocal induction of mesenchymal and neural crest cells.

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