Literature DB >> 895414

Role and mechanism of peripheral fatty acid mobilization in 2-mercaptoethanol-induced fatty liver.

D Sabourault, Y Giudicelli, J Nordmann, R Nordmann.   

Abstract

2-Mercaptoethanol-induced fatty liver involves an increased free fatty acid mobilization which is primarily due to an inhibition of free fatty acid reesterification in adipose tissue. Furthermore, increased free fatty acid mobilization as well as fatty liver induction are not induced by 2-mercaptoethanol per se but result most probably from 2-mercaptoacetate through oxidation of 2-mercaptoethanol.

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Year:  1977        PMID： 895414     DOI： 10.1007/bf02533758

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  15 in total

1.  Improved method for the determination of blood glutathione.

Authors:  E BEUTLER; O DURON; B M KELLY
Journal:  J Lab Clin Med       Date:  1963-05

2.  Metabolic pathways involved in the oxidation of isopropanol into acetone by the intact rat.

Authors:  R Nordmann; C Ribiere; H Rouach; F Beauge; Y Giudicelli; J Nordmann
Journal:  Life Sci       Date:  1973-10-01       Impact factor: 5.037

3.  Enzymes catalysing ethanol metabolism in neural and somatic tissues of the rat.

Authors:  N H Raskin; L Sokoloff
Journal:  J Neurochem       Date:  1972-02       Impact factor: 5.372

4.  Inhibition of ethanol metabolism in vivo by administration of pyrazole.

Authors:  L Goldberg; U Rydberg
Journal:  Biochem Pharmacol       Date:  1969-07       Impact factor: 5.858

5.  Metabolic effects of acetaldehyde on rat adipose tissue in vitro.

Authors:  Y Giudicelli; R Nordmann; J Nordmann
Journal:  Biochim Biophys Acta       Date:  1972-11-30

6.  Effect of pyrazole on lipolysis in vitro.

Authors:  Y Giudicelli; J Nordmann; R Nordmann
Journal:  Biochem Pharmacol       Date:  1972-08-01       Impact factor: 5.858

7.  Studies of the insulin-like actions of thiols upon isolated fat cells.

Authors:  V R Lavis; R H Williams
Journal:  J Biol Chem       Date:  1970-01-10       Impact factor: 5.157

8.  Effects of pyrazole on hepatic function and structure.

Authors:  C S Lieber; E Rubin; L M DeCarli; P Misra; H Gang
Journal:  Lab Invest       Date:  1970-06       Impact factor: 5.662

9.  The enzymic reduction of nicotinamide-adenine dinucleotide by 2-mercaptoethanol.

Authors:  R F Lambe; D C Williams
Journal:  Biochem J       Date:  1965-11       Impact factor: 3.857

10.  Regulation of lipolysis and cyclic AMP synthesis through energy supply in isolated human fat cells.

Authors:  Y Giudicelli; R Pecquery; D Provin; B Agli; R Nordmann
Journal:  Biochim Biophys Acta       Date:  1977-02-23
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  1 in total

1.  2-Mercaptoacetate administration depresses the beta-oxidation pathway through an inhibition of long-chain acyl-CoA dehydrogenase activity.

Authors:  F Bauché; D Sabourault; Y Giudicelli; J Nordmann; R Nordmann
Journal:  Biochem J       Date:  1981-06-15       Impact factor: 3.857
  1 in total

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