| Literature DB >> 8953428 |
P V Tan1, N G Nditafon, M P Yewah, T Dimo, F J Ayafor.
Abstract
The anti-ulcerogenic potential of the aqueous extract of Eremomastax speciosa leaves was investigated using two methods of ulcer induction: HCl/EtOH-induced ulceration and pylorus ligation. With both methods, the extract inhibited gastric ulceration in a dose-related manner. The highest oral dose tested (190 mg/kg) completely inhibited gastric ulceration and significantly reduced gastric acidity compared with the controls. Incubation of gastric juice with the plant extract (190 mg/kg) significantly reduced the acidity of the incubated gastric juice compared with the controls.Entities:
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Year: 1996 PMID： 8953428 DOI： 10.1016/s0378-8741(96)01461-4
Source DB: PubMed Journal: J Ethnopharmacol ISSN： 0378-8741 Impact factor: 4.360