Literature DB >> 8950811

In search of tuberculosis virulence genes.

D M Collins1.   

Abstract

The identity of the virulence genes that enable tuberculosis organisms to survive in macrophages and to induce the features of tuberculosis remains largely unknown. Numerous putative virulence genes have been identified, but so far there is only conclusive evidence for the role of two genes, KatG and rpoV, in virulence.

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Year:  1996        PMID： 8950811     DOI： 10.1016/0966-842x(96)10066-4

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  4 in total

Review 1.  Tuberculous meningitis.

Authors:  G Thwaites; T T Chau; N T Mai; F Drobniewski; K McAdam; J Farrar
Journal:  J Neurol Neurosurg Psychiatry       Date:  2000-03       Impact factor: 10.154

Review 2.  Questions about the behaviour of bacterial pathogens in vivo.

Authors:  H Smith
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2000-05-29       Impact factor: 6.237

3.  An oxyferrous heme/protein-based radical intermediate is catalytically competent in the catalase reaction of Mycobacterium tuberculosis catalase-peroxidase (KatG).

Authors:  Javier Suarez; Kalina Ranguelova; Andrzej A Jarzecki; Julia Manzerova; Vladimir Krymov; Xiangbo Zhao; Shengwei Yu; Leonid Metlitsky; Gary J Gerfen; Richard S Magliozzo
Journal:  J Biol Chem       Date:  2009-01-12       Impact factor: 5.157

4.  Isoniazid resistance without a loss of fitness in Mycobacterium tuberculosis.

Authors:  Jong-Hee Lee; Nicole C Ammerman; Scott Nolan; Deborah E Geiman; Shichun Lun; Haidan Guo; William R Bishai
Journal:  Nat Commun       Date:  2012-03-20       Impact factor: 14.919
  4 in total

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