Literature DB >> 8950174

Isolation and characterization of the Bacillus subtilis tryptophanyl-tRNA synthetase gene (trpS) conferring 5-fluorotryptophan resistance and temperature sensitivity.

K C Chow1, J T Wong.   

Abstract

The mutant trpS gene of Bacillus subtilis encoding a thermosensitive tryptophanyl-tRNA synthetase that also confers resistance to growth inhibition by 5-fluorotryptophan at permissive temperature has been isolated and characterized. A point mutation at codon 82 of the gene from a wild-type TCA codon for Ser to a TTA codon for Leu has been identified.

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Year:  1996        PMID： 8950174     DOI： 10.1016/s0167-4781(96)00136-4

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  3 in total

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Authors:  A L Palombella; S K Dutcher
Journal:  Plant Physiol       Date:  1998-06       Impact factor: 8.340

2.  Selection and characterization of Escherichia coli variants capable of growth on an otherwise toxic tryptophan analogue.

Authors:  J M Bacher; A D Ellington
Journal:  J Bacteriol       Date:  2001-09       Impact factor: 3.490

3.  Mutations enabling displacement of tryptophan by 4-fluorotryptophan as a canonical amino acid of the genetic code.

Authors:  Allen Chi-Shing Yu; Aldrin Kay-Yuen Yim; Wai-Kin Mat; Amy Hin-Yan Tong; Si Lok; Hong Xue; Stephen Kwok-Wing Tsui; J Tze-Fei Wong; Ting-Fung Chan
Journal:  Genome Biol Evol       Date:  2014-03       Impact factor: 3.416
  3 in total

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