Literature DB >> 895010

Interaction of allopurinol with phenprocoumon in man.

E Jähnchen, I Meinertz, H J Gilfrich.   

Abstract

Conditions in two patients on long-term phenprocoumon (Marcumar) treatment are reported who had signs of phenprocoumon overdosage when given simultaneously allopurinol. The determination of phenprocoumon plasma concentrations in one patient showed that phenprocoumon accumulates for several weeks during treatment with allopurinol. Signs of phenprocoumon overdisage thus can appear long time after starting allopurinol treatment.

Entities:  

Mesh：

Substances：

Year:  1977        PMID： 895010     DOI： 10.1007/bf01476963

Source DB:  PubMed          Journal:  Klin Wochenschr        ISSN： 0023-2173


  6 in total

1.  Rapid gas chromatographic determination of underivatized phenprocoumon in plasma.

Authors:  K F Schmitt; E Jähnchen
Journal:  J Chromatogr       Date:  1977-01-11

2.  Impairment of drug metabolism in man by allopurinol and nortriptyline.

Authors:  E S Vesell; G T Passananti; F E Greene
Journal:  N Engl J Med       Date:  1970-12-31       Impact factor: 91.245

3.  Letter: Drug enhancement of warfarin activity.

Authors:  T H Self; W E Evans; T Ferguson
Journal:  Lancet       Date:  1975-09-20       Impact factor: 79.321

4.  Blood levels of drug at the equilibrium state after multiple dosing.

Authors:  J G Wagner; J I Northam; C D Alway; O S Carpenter
Journal:  Nature       Date:  1965-09-18       Impact factor: 49.962

5.  The enantiomers of phenprocoumon: pharmacodynamic and pharmacokinetic studies.

Authors:  E Jähnchen; T Meinertz; H J Gilfrich; U Groth; A Martini
Journal:  Clin Pharmacol Ther       Date:  1976-09       Impact factor: 6.875

6.  Influence of allopurinol on drug metabolism in man.

Authors:  M D Rawlins; S E Smith
Journal:  Br J Pharmacol       Date:  1973-08       Impact factor: 8.739
  6 in total
  2 in total

1.  Bleeding complications and liver injuries during phenprocoumon treatment: a multicentre prospective observational study in internal medicine departments.

Authors:  Sven Schmiedl; Marietta Rottenkolber; Jacek Szymanski; Werner Siegmund; Marion Hippius; Katrin Farker; Bernd Drewelow; Joerg Hasford; Petra Thürmann
Journal:  Dtsch Arztebl Int       Date:  2013-04-05       Impact factor: 5.594

Review 2.  Clinically important drug interactions with anticoagulants. An update.

Authors:  S Harder; P Thürmann
Journal:  Clin Pharmacokinet       Date:  1996-06       Impact factor: 6.447
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.