Literature DB >> 8948485

Role of ionic interactions in cholinesterase catalysis.

V Tõugu1, T Kesvatera.   

Abstract

Acetylcholinesterase (AChE, EC 3.1.1.7) is an enzyme terminating the transmission of nerve impulse in synapses by rapid and selective hydrolysis of the neurotransmitter acetylcholine. Recent years have added a considerable amount of structural knowledge about this protein as well as opened new perspectives to the study of the molecular mechanism of cholinesterase catalysis. In this paper the current state of understanding the molecular recognition by cholinesterases is critically surveyed with particular emphasis on the role of electrostatic interactions.

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Year:  1996        PMID： 8948485     DOI： 10.1016/s0167-4838(96)00128-8

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  10 in total

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2.  Acetylcholinesterase activity in rats experimentally demyelinated with ethidium bromide and treated with interferon beta.

Authors:  C M Mazzanti; R M Spanevello; L B Pereira; J F Gonçalves; R Kaizer; M Corrêa; M Ahmed; A Mazzanti; R Festugatto; D L Graça; V M Morsch; M R C Schetinger
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3.  Expression of cholinergic, insulin, vitamin D receptors and GLUT 3 in the brainstem of streptozotocin induced diabetic rats: effect of treatment with vitamin D₃.

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Journal:  Neurochem Res       Date:  2011-06-26       Impact factor: 3.996

4.  Salting the charged surface: pH and salt dependence of protein G B1 stability.

Authors:  Stina Lindman; Wei-Feng Xue; Olga Szczepankiewicz; Mikael C Bauer; Hanna Nilsson; Sara Linse
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5.  Evaluation of acetylcholinesterase in an animal model of maple syrup urine disease.

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6.  Biochemical Marker Assessment of Chronic Carbamazepine Exposure at Environmentally Relevant Concentrations in Juvenile Common Carp (Cyprinus carpio).

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Journal:  Antioxidants (Basel)       Date:  2022-06-09

7.  Kinetically-controlled mechanism-based isolation of metabolic serine hydrolases in active form from complex proteomes: butyrylcholinesterase as a case study.

Authors:  Hui Liu; Huimin Zhou; Huaqiao Du; Qiaoling Xiao; Marco Pistolozzi
Journal:  RSC Adv       Date:  2019-11-26       Impact factor: 4.036

Review 8.  "Manganese-induced neurotoxicity: a review of its behavioral consequences and neuroprotective strategies".

Authors:  Tanara V Peres; Maria Rosa C Schettinger; Pan Chen; Fabiano Carvalho; Daiana S Avila; Aaron B Bowman; Michael Aschner
Journal:  BMC Pharmacol Toxicol       Date:  2016-11-04       Impact factor: 2.483

9.  Development and Molecular Investigation into the Effects of Carbamazepine Exposure in the Zebrafish (Danio rerio).

Authors:  Huihui Chen; Huiting Yang; Yanyan Zhao; Xiaohong Gu; Christopher J Martyniuk
Journal:  Int J Environ Res Public Health       Date:  2020-11-29       Impact factor: 3.390

10.  Evaluation of a Brain Acetylcholinesterase Extraction Method and Kinetic Constants after Methyl-Paraoxon Inhibition in Three Brazilian Fish Species.

Authors:  A P Freitas; C R Santos; P N Sarcinelli; M V Silva Filho; R A Hauser-Davis; R M Lopes
Journal:  PLoS One       Date:  2016-09-21       Impact factor: 3.240
  10 in total

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