Literature DB >> 8946752

Sclerotiamide: a new member of the paraherquamide class with potent antiinsectan activity from the sclerotia of Aspergillus sclerotiorum.

A C Whyte1, J B Gloer, D T Wicklow, P F Dowdw.   

Abstract

Sclerotiamide (1), a new fungal natural product related to the paraherquamides, was isolated by bioassay-guided fractionation of antiinsectan organic extracts from the sclerotia of Aspergillus sclerotiorum (NRRL 5167). The structure was determined primarily through 1H-NMR, 13C-NMR, HMQC, and HMBC experiments. Sclerotiamide causes significant mortality and unusual physiological effects in dietary assays against the corn earworm Helicoverpa zea.

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Year:  1996        PMID： 8946752     DOI： 10.1021/np960607m

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  30 in total

1.  Waikialoid A suppresses hyphal morphogenesis and inhibits biofilm development in pathogenic Candida albicans.

Authors:  Xiaoru Wang; Jianlan You; Jarrod B King; Douglas R Powell; Robert H Cichewicz
Journal:  J Nat Prod       Date:  2012-03-08       Impact factor: 4.050

2.  Studies Towards Paraherquamides E & F and Related C-labeled Putative Biosynthetic Intermediates: Stereocontrolled Synthesis of the α-Alkyl-β-Methylproline Ring System.

Authors:  Konrad Sommer; Robert M Williams
Journal:  Tetrahedron       Date:  2008-07-21       Impact factor: 2.457

3.  Studies on the Biosynthesis of the Stephacidin and Notoamide Natural Products: A Stereochemical and Genetic Conundrum.

Authors:  James D Sunderhaus; David H Sherman; Robert M Williams
Journal:  Isr J Chem       Date:  2011-04       Impact factor: 3.333

4.  Isolation, structure elucidation, and biomimetic total synthesis of versicolamide B, and the isolation of antipodal (-)-stephacidin A and (+)-notoamide B from Aspergillus versicolor NRRL 35600.

Authors:  Thomas J Greshock; Alan W Grubbs; Ping Jiao; Donald T Wicklow; James B Gloer; Robert M Williams
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

Review 5.  Natural products synthesis: enabling tools to penetrate Nature's secrets of biogenesis and biomechanism.

Authors:  Robert M Williams
Journal:  J Org Chem       Date:  2011-04-12       Impact factor: 4.354

6.  Beyond aflatoxin: four distinct expression patterns and functional roles associated with Aspergillus flavus secondary metabolism gene clusters.

Authors:  D Ryan Georgianna; Natalie D Fedorova; James L Burroughs; Andrea L Dolezal; Jin Woo Bok; Sigal Horowitz-Brown; Charles P Woloshuk; Jiujiang Yu; Nancy P Keller; Gary A Payne
Journal:  Mol Plant Pathol       Date:  2010-03       Impact factor: 5.663

Review 7.  Spatial and temporal control of fungal natural product synthesis.

Authors:  Fang Yun Lim; Nancy P Keller
Journal:  Nat Prod Rep       Date:  2014-10       Impact factor: 13.423

8.  Ochratoxin production and taxonomy of the yellow aspergilli (Aspergillus section Circumdati).

Authors:  C M Visagie; J Varga; J Houbraken; M Meijer; S Kocsubé; N Yilmaz; R Fotedar; K A Seifert; J C Frisvad; R A Samson
Journal:  Stud Mycol       Date:  2014-06       Impact factor: 16.097

9.  Flavin-Dependent Monooxygenases NotI and NotI' Mediate Spiro-Oxindole Formation in Biosynthesis of the Notoamides.

Authors:  Amy E Fraley; Hong T Tran; Samantha P Kelly; Sean A Newmister; Ashootosh Tripathi; Hikaru Kato; Sachiko Tsukamoto; Lei Du; Shengying Li; Robert M Williams; David H Sherman
Journal:  Chembiochem       Date:  2020-05-14       Impact factor: 3.164

10.  Isolation of notoamide E, a key precursor in the biosynthesis of prenylated indole alkaloids in a marine-derived fungus, Aspergillus sp.

Authors:  Sachiko Tsukamoto; Hikaru Kato; Thomas J Greshock; Hiroshi Hirota; Tomihisa Ohta; Robert M Williams
Journal:  J Am Chem Soc       Date:  2009-03-25       Impact factor: 15.419
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