Literature DB >> 8945784

Two new monoterpene glycosides from ku-ding-cha. Inhibitors of acyl-CoA: cholesterol acyltransferase (ACAT).

T Fukuda1, Y Kitada, X M Chen, L Yang, T Miyase.   

Abstract

Two new monoterpene glycosides, kudingosides A and B, were isolated from Ku-Ding-Cha (Ligustrum pedunculare REHD.), together with a known monoterpene glycoside, (S)-lipedoside B-III, and three known phenylethanoid glycosides. Their structures were elucidated by spectroscopic and chemical means. Kudingosides A and B, and (S)-lipedoside B-III inhibited acyl-CoA: cholesterol acyltransferase (ACAT) with IC50 values of 2.70 x 10(-3)M, 2.88 x 10(-3)M, and 2.69 x 10(-4)M, respectively.

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Year:  1996        PMID: 8945784     DOI: 10.1248/cpb.44.2173

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  2 in total

Review 1.  Astonishing diversity of natural surfactants: 7. Biologically active hemi- and monoterpenoid glycosides.

Authors:  Valery M Dembitsky
Journal:  Lipids       Date:  2006-01       Impact factor: 1.880

2.  Two new monoterpene glycosides from Qing Shan Lu Shui tea with inhibitory effects on leukocyte-type 12-lipoxygenase activity.

Authors:  Hideyuki Ito; Akemi Otsuki; Hitomi Mori; Peng Li; Mai Kinoshita; Yuki Kawakami; Hideaki Tsuji; Ding Zhi Fang; Yoshitaka Takahashi
Journal:  Molecules       Date:  2013-04-11       Impact factor: 4.411

  2 in total

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