Literature DB >> 8944588

Accuracy of four automatic QT measurement techniques in cardiac patients and healthy subjects.

N B McLaughlin1, R W Campbell, A Murray.   

Abstract

OBJECTIVE: To assess differences in the accuracy of automatic QT measurement in three subject groups, and to determine the influence of T wave amplitude on these measurements.
SUBJECTS: Standard simultaneous 12 lead electrocardiograms were acquired from 25 patients post myocardial infarction, 25 with arrhythmias, and 25 controls.
DESIGN: Because there is not yet a standard automatic method for QT analysis, four different techniques were used. Manual QT measurements were used as the reference. QT was measured in two complexes by each technique in each lead, subject, and group. MAIN OUTCOME MEASURE: The differences between reference and automatic QT measurements from the three subject groups were compared independently for the four techniques. The T wave amplitudes for each of the groups were also compared.
RESULTS: Variability of the automatic QT measurements, relative to the manual reference, in the cardiac patients was 2.1 times that in the controls (P < 0.005). Mean T wave amplitude was lower (by a factor of two) for the cardiac patients compared with the controls (P < 0.01). No simple relation between T wave amplitude and the difference between automatic and manual QT measurements was found, although the difference was 2.2 times greater for absolute T wave amplitudes of less than 0.25 mV (P < 0.001).
CONCLUSIONS: Automatic QT measurement techniques are less accurate in cardiac patients than in controls. Measurements from T waves with amplitudes less than 0.25 mV are less reliable.

Entities:  

Mesh:

Year:  1996        PMID: 8944588      PMCID: PMC484574          DOI: 10.1136/hrt.76.5.422

Source DB:  PubMed          Journal:  Heart        ISSN: 1355-6037            Impact factor:   5.994


  10 in total

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4.  Comparison of QT dispersion in hypertrophic cardiomyopathy between patients with and without ventricular arrhythmias and sudden death.

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Authors:  J O'Donnell; D E Lovelace; S B Knoebel; P L McHenry
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9.  QT dispersion: an indication of arrhythmia risk in patients with long QT intervals.

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10.  QT dispersion and sudden unexpected death in chronic heart failure.

Authors:  C S Barr; A Naas; M Freeman; C C Lang; A D Struthers
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  10 in total
  19 in total

1.  Measuring QT dispersion: man versus machine.

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8.  QT dispersion in patients with acromegaly.

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9.  Highly automated QT measurement techniques in 7 thorough QT studies implemented under ICH E14 guidelines.

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10.  Relation between QT duration and maximal wall thickness in familial hypertrophic cardiomyopathy.

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