F H Rampen1, P M Steijlen. 1. Department of Dermatology, Sint Anna Hospital, Oss, The Netherlands.
Abstract
BACKGROUND: Induction of delayed-type hypersensitivity has recently been introduced for resistant viral warts. The method is not painful and less destructive than most other modalities. OBJECTIVE: We assessed the efficacy of topical diphencyprone (diphenylcyclopropenone) treatment for recalcitrant warts. METHODS: From September 1988 to June 1995, 134 patients with periungual and/or palmoplantar warts were entered into the study. Eight weekly applications were delivered. RESULTS: The scheduled treatment course and follow-up were completed by 111 patients. There were 49 complete and 18 partial remissions. The rate of positive responders (60%) compares with the results published by other authors. CONCLUSION: Diphencyprone is an effective treatment for resistant warts, especially in palmoplantar and periungual locations.
BACKGROUND: Induction of delayed-type hypersensitivity has recently been introduced for resistant viral warts. The method is not painful and less destructive than most other modalities. OBJECTIVE: We assessed the efficacy of topical diphencyprone (diphenylcyclopropenone) treatment for recalcitrant warts. METHODS: From September 1988 to June 1995, 134 patients with periungual and/or palmoplantar warts were entered into the study. Eight weekly applications were delivered. RESULTS: The scheduled treatment course and follow-up were completed by 111 patients. There were 49 complete and 18 partial remissions. The rate of positive responders (60%) compares with the results published by other authors. CONCLUSION:Diphencyprone is an effective treatment for resistant warts, especially in palmoplantar and periungual locations.