Literature DB >> 8942550

T1 breast carcinoma in women 70 years of age and older may not require axillary lymph node dissection.

B J Feigelson1, J A Acosta, H S Feigelson, A Findley, E L Saunders.   

Abstract

BACKGROUND: The current trend in breast cancer treatment is toward breast conservation and selective use of axillary lymph node dissection. Patient eligibility criteria for treatment without axillary dissection are evolving.
METHODS: We retrospectively reviewed the tumor registry over a 10-year period at Naval Medical Center San Diego and included all women aged 70 and older with T1 breast carcinoma (n = 78). Data included tumor size, surgical therapy, post-operative therapy, recurrence, and survival. The women were divided into groups by the approach taken toward the axilla.
RESULTS: No patient was given adjuvant chemotherapy. There were no axillary cancer recurrences in our patients. No statistically significant difference existed, regardless of the approach to the axilla, in recurrence or survival between groups.
CONCLUSION: Axillary dissection in this population did not influence postoperative treatment, decrease recurrence, or improve survival. Our study suggests breast cancer treatment in this population should not include axillary dissection.

Entities:  

Mesh:

Year:  1996        PMID: 8942550     DOI: 10.1016/S0002-9610(96)00249-8

Source DB:  PubMed          Journal:  Am J Surg        ISSN: 0002-9610            Impact factor:   2.565


  4 in total

1.  Predictors and outcomes of completion axillary node dissection among older breast cancer patients.

Authors:  Sara H Javid; Hao He; Larissa A Korde; David R Flum; Benjamin O Anderson
Journal:  Ann Surg Oncol       Date:  2014-03-01       Impact factor: 5.344

2.  Stage and treatment variation with age in postmenopausal women with breast cancer: compliance with guidelines.

Authors:  L Wyld; D K Garg; I D Kumar; H Brown; M W R Reed
Journal:  Br J Cancer       Date:  2004-04-19       Impact factor: 7.640

3.  Socioeconomic deprivation worsens the outcomes of Italian women with hormone receptor-positive breast cancer and decreases the possibility of receiving standard care.

Authors:  Francesca Di Salvo; Nicola Caranci; Teresa Spadea; Nicolas Zengarini; Pamela Minicozzi; Hade Amash; Mario Fusco; Fabrizio Stracci; Fabio Falcini; Claudia Cirilli; Giuseppina Candela; Rosanna Cusimano; Rosario Tumino; Milena Sant
Journal:  Oncotarget       Date:  2017-07-22

4.  Axillary dissection versus axillary observation for low risk, clinically node-negative invasive breast cancer: a systematic review and meta-analysis.

Authors:  Mahaveer S Sangha; Rose Baker; Muneer Ahmed
Journal:  Breast Cancer       Date:  2021-07-09       Impact factor: 4.239

  4 in total

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