Literature DB >> 8941337

Molecular cloning of the mouse activin beta E subunit gene.

J Fang1, W Yin, E Smiley, S Q Wang, J Bonadio.   

Abstract

cDNA clones encoding a novel activin beta subunit have been isolated from mouse liver cDNA library. An amino acid homology comparison among members of the TGF-beta superfamily indicates that the open reading frame codes for a new activin/inhibin beta subunit. The predicted mature region of the subunit shows > 60% identity with activin beta C and beta D and > or = 45% identity with activin beta A and beta B, but only 20-40% amino acid sequence identity with other TGF-beta superfamily members. Therefore, the novel subunit has been designated activin beta E. Alignment of the mature growth factor region of the five activin beta subunits revealed that activin beta A and beta B share 63% amino acid identity, while activin beta C, beta D, and beta E share 62% identity. Therefore, activin beta A and beta B are most related to one another, while activin beta C, beta D, and beta E may represent a subset of related sequences.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 8941337     DOI： 10.1006/bbrc.1996.1715

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  16 in total

1.  Immunohistochemical labeling of the inhibin/activin betaC subunit in normal human placental tissue and chorionic carcinoma cell lines.

Authors:  Tobias Weissenbacher; Ansgar Brüning; Tanja Kimmich; Josef Makovitzky; Andrea Gingelmaier; Ioannis Mylonas
Journal:  J Histochem Cytochem       Date:  2010-05-10       Impact factor: 2.479

Review 2.  Hippocampal plasticity involves extensive gene induction and multiple cellular mechanisms.

Authors:  D Hevroni; A Rattner; M Bundman; D Lederfein; A Gabarah; M Mangelus; M A Silverman; H Kedar; C Naor; M Kornuc; T Hanoch; R Seger; L E Theill; E Nedivi; G Richter-Levin; Y Citri
Journal:  J Mol Neurosci       Date:  1998-04       Impact factor: 3.444

Review 3.  Activins and Inhibins: Roles in Development, Physiology, and Disease.

Authors:  Maria Namwanje; Chester W Brown
Journal:  Cold Spring Harb Perspect Biol       Date:  2016-07-01       Impact factor: 10.005

4.  Impaired wound healing in transgenic mice overexpressing the activin antagonist follistatin in the epidermis.

Authors:  M Wankell; B Munz; G Hübner; W Hans; E Wolf; A Goppelt; S Werner
Journal:  EMBO J       Date:  2001-10-01       Impact factor: 11.598

5.  Activin betaC and betaE genes are not essential for mouse liver growth, differentiation, and regeneration.

Authors:  A L Lau; T R Kumar; K Nishimori; J Bonadio; M M Matzuk
Journal:  Mol Cell Biol       Date:  2000-08       Impact factor: 4.272

6.  Inhibin/activin subunits alpha, beta-A and beta-B are differentially expressed in normal human endometrium throughout the menstrual cycle.

Authors:  Ioannis Mylonas; Udo Jeschke; Irmgard Wiest; Anna Hoeing; Julia Vogl; Naim Shabani; Christina Kuhn; Sandra Schulze; Markus S Kupka; Klaus Friese
Journal:  Histochem Cell Biol       Date:  2004-10-12       Impact factor: 4.304

7.  Rat activin-betaE mRNA expression during development and in acute and chronic liver injury.

Authors:  Elspeth J Gold; Marcel A Monaghan; Jean S Fleming
Journal:  J Mol Genet Med       Date:  2006-04-12

8.  Phylogenomic analyses reveal the evolutionary origin of the inhibin alpha-subunit, a unique TGFbeta superfamily antagonist.

Authors:  Jie Zhu; Edward L Braun; Satomi Kohno; Monica Antenos; Eugene Y Xu; Robert W Cook; S Jack Lin; Brandon C Moore; Louis J Guillette; Theodore S Jardetzky; Teresa K Woodruff
Journal:  PLoS One       Date:  2010-03-04       Impact factor: 3.240

Review 9.  Activins and activin antagonists in hepatocellular carcinoma.

Authors:  Alev Deli; Emanuel Kreidl; Stefan Santifaller; Barbara Trotter; Katja Seir; Walter Berger; Rolf Schulte-Hermann; Chantal Rodgarkia-Dara; Michael Grusch
Journal:  World J Gastroenterol       Date:  2008-03-21       Impact factor: 5.742

10.  Changes in the reproductive function and developmental phenotypes in mice following intramuscular injection of an activin betaA-expressing plasmid.

Authors:  Mi-Nyeu Kim; Moon Nyeo Park; Hoi Kyung Jung; Chunghee Cho; Kelly E Mayo; Byung-Nam Cho
Journal:  Reprod Biol Endocrinol       Date:  2008-12-16       Impact factor: 5.211
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.