OBJECTIVE: To evaluate the effectiveness of IVF treatment in endometriosis-associated infertility. DESIGN: Nonrandom retrospective study. SETTING: Department of Gynecology and Obstetrics, Akita University School of Medicine. MAIN OUTCOME MEASURE(S): Cumulative pregnancy rate. PATIENT(S): One hundred eighteen infertile patients in whom diagnosis of endometriosis was established by laparoscopic examination. INTERVENTION(S): The prognoses of 60 patients (IVF group) who started IVF treatment within 6 months after laparoscopy were compared with those of 58 patients who were managed expectantly without IVF treatment during the same period. RESULT(S): The cumulative conception rates at 36 months after laparoscopy were 62% in the IVF group and 43% in the control group, and the difference was not significant (a log-rank test). For patients > or = 32 years of age, the conception rates were significantly higher in the IVF group (59% versus 29%). A relatively large but nonsignificant difference in the conception rate between the two groups was observed in patients with endometriosis at stages III or IV (52% versus 27%). CONCLUSION(S): In vitro fertilization treatment provides better prognosis in patients > or = 32 years of age and is recommended for such patients. The benefits of treatment appear to be greater in patients with more advanced stages of endometriosis.
OBJECTIVE: To evaluate the effectiveness of IVF treatment in endometriosis-associated infertility. DESIGN: Nonrandom retrospective study. SETTING: Department of Gynecology and Obstetrics, Akita University School of Medicine. MAIN OUTCOME MEASURE(S): Cumulative pregnancy rate. PATIENT(S): One hundred eighteen infertilepatients in whom diagnosis of endometriosis was established by laparoscopic examination. INTERVENTION(S): The prognoses of 60 patients (IVF group) who started IVF treatment within 6 months after laparoscopy were compared with those of 58 patients who were managed expectantly without IVF treatment during the same period. RESULT(S): The cumulative conception rates at 36 months after laparoscopy were 62% in the IVF group and 43% in the control group, and the difference was not significant (a log-rank test). For patients > or = 32 years of age, the conception rates were significantly higher in the IVF group (59% versus 29%). A relatively large but nonsignificant difference in the conception rate between the two groups was observed in patients with endometriosis at stages III or IV (52% versus 27%). CONCLUSION(S): In vitro fertilization treatment provides better prognosis in patients > or = 32 years of age and is recommended for such patients. The benefits of treatment appear to be greater in patients with more advanced stages of endometriosis.
Authors: U Ulrich; O Buchweitz; R Greb; J Keckstein; I von Leffern; P Oppelt; S P Renner; M Sillem; W Stummvoll; R-L De Wilde; K-W Schweppe Journal: Geburtshilfe Frauenheilkd Date: 2014-12 Impact factor: 2.915
Authors: U Ulrich; O Buchweitz; R Greb; J Keckstein; I von Leffern; P Oppelt; S P Renner; M Sillem; W Stummvoll; K-W Schweppe Journal: Geburtshilfe Frauenheilkd Date: 2013-09 Impact factor: 2.915