Literature DB >> 8939674

Pax genes and their roles in cell differentiation and development.

A Mansouri1, M Hallonet, P Gruss.   

Abstract

Members of the Pax gene family are expressed in various tissues during ontogenesis. Evidence for their crucial role in morphogenesis, organogenesis, cell differentiation and oncogenesis is provided by rodent mutants and human diseases. Additionally, recent experimental in vivo and in vitro approaches have led to the identification of molecules that interact with Pax proteins.

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Year:  1996        PMID: 8939674     DOI: 10.1016/s0955-0674(96)80087-1

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN: 0955-0674            Impact factor:   8.382


  68 in total

1.  Id helix-loop-helix proteins antagonize pax transcription factor activity by inhibiting DNA binding.

Authors:  E C Roberts; R W Deed; T Inoue; J D Norton; A D Sharrocks
Journal:  Mol Cell Biol       Date:  2001-01       Impact factor: 4.272

2.  Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding.

Authors:  H E Xu; M A Rould; W Xu; J A Epstein; R L Maas; C O Pabo
Journal:  Genes Dev       Date:  1999-05-15       Impact factor: 11.361

3.  Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers.

Authors:  Attila Reményi; Katharina Lins; L Johan Nissen; Rolland Reinbold; Hans R Schöler; Matthias Wilmanns
Journal:  Genes Dev       Date:  2003-08-15       Impact factor: 11.361

4.  WBP-2, a WW domain binding protein, interacts with the thyroid-specific transcription factor Pax8.

Authors:  Roberto Nitsch; Tina Di Palma; Anna Mascia; Mariastella Zannini
Journal:  Biochem J       Date:  2004-02-01       Impact factor: 3.857

5.  Facilitated DNA search by multidomain transcription factors: cross talk via a flexible linker.

Authors:  Dana Vuzman; Michal Polonsky; Yaakov Levy
Journal:  Biophys J       Date:  2010-08-09       Impact factor: 4.033

6.  Sumoylation activates the transcriptional activity of Pax-6, an important transcription factor for eye and brain development.

Authors:  Qin Yan; Lili Gong; Mi Deng; Lan Zhang; Shuming Sun; Jiao Liu; Haili Ma; Dan Yuan; Pei-Chao Chen; Xiaohui Hu; Jinping Liu; Jichao Qin; Ling Xiao; Xiao-Qin Huang; Jian Zhang; David Wan-Cheng Li
Journal:  Proc Natl Acad Sci U S A       Date:  2010-11-17       Impact factor: 11.205

Review 7.  Myogenesis and muscle regeneration.

Authors:  Faisal Yusuf; Beate Brand-Saberi
Journal:  Histochem Cell Biol       Date:  2012-05-27       Impact factor: 4.304

8.  Specification of the mammalian cochlea is dependent on Sonic hedgehog.

Authors:  Martin M Riccomagno; Lenka Martinu; Michael Mulheisen; Doris K Wu; Douglas J Epstein
Journal:  Genes Dev       Date:  2002-09-15       Impact factor: 11.361

9.  Maternal transmission effects of the PAX genes among cleft case-parent trios from four populations.

Authors:  Jae Woong Sull; Kung-Yee Liang; Jacqueline B Hetmanski; Margaret Daniele Fallin; Roxanne G Ingersoll; Jiwan Park; Yah-Huei Wu-Chou; Philip K Chen; Samuel S Chong; Felicia Cheah; Vincent Yeow; Beyoung Yun Park; Sun Ha Jee; Ethylin W Jabs; Richard Redett; Alan F Scott; Terri H Beaty
Journal:  Eur J Hum Genet       Date:  2009-01-14       Impact factor: 4.246

10.  Linkage to chromosome 2q36.1 in autosomal dominant Dandy-Walker malformation with occipital cephalocele and evidence for genetic heterogeneity.

Authors:  Ali Jalali; Kimberly A Aldinger; Ajit Chary; David G McLone; Robin M Bowman; Luan Cong Le; Phillip Jardine; Ruth Newbury-Ecob; Andrew Mallick; Nadereh Jafari; Eric J Russell; John Curran; Pam Nguyen; Karim Ouahchi; Charles Lee; William B Dobyns; Kathleen J Millen; Joao M Pina-Neto; John A Kessler; Alexander G Bassuk
Journal:  Hum Genet       Date:  2008-01-19       Impact factor: 4.132

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