Literature DB >> 8939661

Integrins and cancer.

J A Varner1, D A Cheresh.   

Abstract

The past year or two has seen great advances in the elucidation of significant roles for integrins in cancer cells. These include roles in signal transduction, gene expression, proliferation, apoptosis regulation, invasion and metastasis, and angiogenesis. In particular, integrin alphavbeta3 has been implicated in the neovascularization of tumors. In addition, this integrin has been shown to contribute to the survival, proliferation and metastatic phenotype of human melanoma.

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Year:  1996        PMID： 8939661     DOI： 10.1016/s0955-0674(96)80115-3

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN： 0955-0674            Impact factor:   8.382


  113 in total

Review 1.  Order and disorder: the role of extracellular matrix in epithelial cancer.

Authors:  Derek Radisky; John Muschler; Mina J Bissell
Journal:  Cancer Invest       Date:  2002       Impact factor: 2.176

2.  Cross talk between beta(1) and alpha(V) integrins: beta(1) affects beta(3) mRNA stability.

Authors:  S F Retta; G Cassarà; M D'Amato; R Alessandro; M Pellegrino; S Degani; G De Leo; L Silengo; G Tarone
Journal:  Mol Biol Cell       Date:  2001-10       Impact factor: 4.138

3.  Urokinase-receptor/integrin complexes are functionally involved in adhesion and progression of human breast cancer in vivo.

Authors:  G van der Pluijm; B Sijmons; H Vloedgraven; C van der Bent; J W Drijfhout; J Verheijen; P Quax; M Karperien; S Papapoulos; C Löwik
Journal:  Am J Pathol       Date:  2001-09       Impact factor: 4.307

4.  A randomized phase II study of cilengitide (EMD 121974) in patients with metastatic melanoma.

Authors:  Kevin B Kim; Victor Prieto; Richard W Joseph; Abdul H Diwan; Gary E Gallick; Nicholas E Papadopoulos; Agop Y Bedikian; Luis H Camacho; Patrick Hwu; Chaan S Ng; Wei Wei; Marcella M Johnson; Sabine M Wittemer; Anna Vardeleon; Aaron Reckeweg; A Dimitrios Colevas
Journal:  Melanoma Res       Date:  2012-08       Impact factor: 3.599

5.  Integrin antagonist augments the therapeutic effect of adenovirus-mediated REIC/Dkk-3 gene therapy for malignant glioma.

Authors:  Y Shimazu; K Kurozumi; T Ichikawa; K Fujii; M Onishi; J Ishida; T Oka; M Watanabe; Y Nasu; H Kumon; I Date
Journal:  Gene Ther       Date:  2014-11-13       Impact factor: 5.250

6.  Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis.

Authors:  Q Yu; I Stamenkovic
Journal:  Genes Dev       Date:  2000-01-15       Impact factor: 11.361

7.  Correlation between biological activity and binding energy in systems of integrin with cyclic RGD-containing binders: a QM/MM molecular dynamics study.

Authors:  Mingli Xiang; Yuchun Lin; Gu He; Lijuan Chen; Mingli Yang; Shengyong Yang; Yirong Mo
Journal:  J Mol Model       Date:  2012-06-27       Impact factor: 1.810

8.  Expression of cholecystokinin-2/gastrin receptor in the murine pancreas modulates cell adhesion and cell differentiation in vivo.

Authors:  Christiane Bierkamp; Stéphanie Bonhoure; Anne Mathieu; Pascal Clerc; Daniel Fourmy; Lucien Pradayrol; Catherine Seva; Marlène Dufresne
Journal:  Am J Pathol       Date:  2004-12       Impact factor: 4.307

9.  Retroviral transfer of antisense integrin alpha6 or alpha8 sequences results in laminar redistribution or clonal cell death in developing brain.

Authors:  Z Zhang; D S Galileo
Journal:  J Neurosci       Date:  1998-09-01       Impact factor: 6.167

10.  Expression of focal adhesion kinase and alpha5 and beta1 integrins in carcinomas and its clinical significance.

Authors:  Jian-Min Su; Lu Gui; Yi-Ping Zhou; Xi-Liang Zha
Journal:  World J Gastroenterol       Date:  2002-08       Impact factor: 5.742
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