Literature DB >> 8939651

Genetic analyses of integrin function in mice.

R Fässler1, E Georges-Labouesse, E Hirsch.   

Abstract

Recent mutations of most integrin genes in the mouse have provided new exciting insights into the role of these integrins in cell-extracellular matrix interactions during development. The embryonic lethal phenotypes obtained by ablating integrins which are predominantly expressed in the mesenchyme confirmed the essential function of those integrins in morphogenesis. In contrast, null alleles for several epithelial integrins which bind components of basement membranes showed milder phenotypes, suggesting the presence of novel and unexpected redundant and compensatory mechanisms.

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Year:  1996        PMID： 8939651     DOI： 10.1016/s0955-0674(96)80105-0

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN： 0955-0674            Impact factor:   8.382


  26 in total

1.  Cross talk between beta(1) and alpha(V) integrins: beta(1) affects beta(3) mRNA stability.

Authors:  S F Retta; G Cassarà; M D'Amato; R Alessandro; M Pellegrino; S Degani; G De Leo; L Silengo; G Tarone
Journal:  Mol Biol Cell       Date:  2001-10       Impact factor: 4.138

2.  Integrins regulate responsiveness to slit repellent signals.

Authors:  Adrienne Stevens; J Roger Jacobs
Journal:  J Neurosci       Date:  2002-06-01       Impact factor: 6.167

3.  Coordinate integrin and c-Met signaling regulate Wnt gene expression during epithelial morphogenesis.

Authors:  Yingjie Liu; Nibedita Chattopadhyay; Shan Qin; Charles Szekeres; Tetyana Vasylyeva; Zhen X Mahoney; Mary Taglienti; Carlton M Bates; Harold A Chapman; Jeffrey H Miner; Jordan A Kreidberg
Journal:  Development       Date:  2009-01-28       Impact factor: 6.868

4.  Regulation of keratin and integrin gene expression in cancer and drug resistance.

Authors:  N Daly; P Meleady; D Walsh; M Clynes
Journal:  Cytotechnology       Date:  1998-09       Impact factor: 2.058

5.  The primitive endoderm segregates from the epiblast in β1 integrin-deficient early mouse embryos.

Authors:  Robert Moore; Wensi Tao; Elizabeth R Smith; Xiang-Xi Xu
Journal:  Mol Cell Biol       Date:  2013-11-25       Impact factor: 4.272

Review 6.  Cellular and molecular partners involved in gut morphogenesis and differentiation.

Authors:  M Kedinger; O Lefebvre; I Duluc; J N Freund; P Simon-Assmann
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1998-06-29       Impact factor: 6.237

7.  Positional importance of Pro53 adjacent to the Arg49-Gly50-Asp51 sequence of rhodostomin in binding to integrin alphaIIbbeta3.

Authors:  C P Chang; J C Chang; H H Chang; W J Tsai; S J Lo
Journal:  Biochem J       Date:  2001-07-01       Impact factor: 3.857

8.  β4 integrin marks interstitial myogenic progenitor cells in adult murine skeletal muscle.

Authors:  Kalliopi Liadaki; Juan Carlos Casar; McKenzie Wessen; Eric S Luth; Susan Jun; Emanuela Gussoni; Louis M Kunkel
Journal:  J Histochem Cytochem       Date:  2012-01       Impact factor: 2.479

9.  Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis.

Authors:  Jing Gao; Mindy C DeRouen; Chih-Hsin Chen; Michael Nguyen; Ngon T Nguyen; Hiroyuki Ido; Kenji Harada; Kiyotoshi Sekiguchi; Bruce A Morgan; Jeffery H Miner; Anthony E Oro; M Peter Marinkovich
Journal:  Genes Dev       Date:  2008-08-01       Impact factor: 11.361

10.  Beta1-integrin signaling is essential for lens fiber survival.

Authors:  Andrew R Samuelsson; Richard Belvindrah; Chuanyue Wu; Uli Müller; Willi Halfter
Journal:  Gene Regul Syst Bio       Date:  2007-10-12
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