Literature DB >> 8939640

Selection of biologically active peptides by phage display of random peptide libraries.

R Cortese1, P Monaci, A Luzzago, C Santini, F Bartoli, I Cortese, P Fortugno, G Galfrè, A Nicosia, F Felici.   

Abstract

Random peptide libraries displayed on phage are used as a source of peptides for epitope mapping, for the identification of critical amino acids responsible for protein-protein interactions and as leads for the discovery of new therapeutics. Efficient and simple procedures have been devised to select peptides binding to purified proteins, to monoclonal and polyclonal antibodies and to cell surfaces in vivo and in vitro.

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Year:  1996        PMID： 8939640     DOI： 10.1016/s0958-1669(96)80072-3

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN： 0958-1669            Impact factor:   9.740


  23 in total

1.  The rational design of a 'type 88' genetically stable peptide display vector in the filamentous bacteriophage fd.

Authors:  D Enshell-Seijffers; L Smelyanski; J M Gershoni
Journal:  Nucleic Acids Res       Date:  2001-05-15       Impact factor: 16.971

2.  Selecting open reading frames from DNA.

Authors:  Paola Zacchi; Daniele Sblattero; Fiorella Florian; Roberto Marzari; Andrew R M Bradbury
Journal:  Genome Res       Date:  2003-05       Impact factor: 9.043

3.  Biotin-tagged cDNA expression libraries displayed on lambda phage: a new tool for the selection of natural protein ligands.

Authors:  Helenia Ansuini; Carla Cicchini; Alfredo Nicosia; Marco Tripodi; Riccardo Cortese; Alessandra Luzzago
Journal:  Nucleic Acids Res       Date:  2002-08-01       Impact factor: 16.971

4.  Prevention of passively transferred experimental autoimmune myasthenia gravis by a phage library-derived cyclic peptide.

Authors:  N Venkatesh; S H Im; M Balass; S Fuchs; E Katchalski-Katzir
Journal:  Proc Natl Acad Sci U S A       Date:  2000-01-18       Impact factor: 11.205

Review 5.  Enhanced prospects for drug delivery and brain targeting by the choroid plexus-CSF route.

Authors:  Conrad E Johanson; John A Duncan; Edward G Stopa; Andrew Baird
Journal:  Pharm Res       Date:  2005-07-22       Impact factor: 4.200

6.  Monocyte activation in angiogenesis and collateral growth in the rabbit hindlimb.

Authors:  M Arras; W D Ito; D Scholz; B Winkler; J Schaper; W Schaper
Journal:  J Clin Invest       Date:  1998-01-01       Impact factor: 14.808

7.  Identification of a peptide blocking vascular endothelial growth factor (VEGF)-mediated angiogenesis.

Authors:  R Binétruy-Tournaire; C Demangel; B Malavaud; R Vassy; S Rouyre; M Kraemer; J Plouët; C Derbin; G Perret; J C Mazié
Journal:  EMBO J       Date:  2000-04-03       Impact factor: 11.598

8.  Identifying epitopes responsible for neutralizing antibody and DC-SIGN binding on the spike glycoprotein of the severe acute respiratory syndrome coronavirus.

Authors:  Yi-Ping Shih; Chia-Yen Chen; Shih-Jen Liu; Kuan-Hsuan Chen; Yuan-Ming Lee; Yu-Chan Chao; Yi-Ming Arthur Chen
Journal:  J Virol       Date:  2006-11       Impact factor: 5.103

9.  The epitopes for natural polyreactive antibodies are rich in proline.

Authors:  B Tchernychev; S Cabilly; M Wilchek
Journal:  Proc Natl Acad Sci U S A       Date:  1997-06-10       Impact factor: 11.205

10.  An artificial cell-cycle inhibitor isolated from a combinatorial library.

Authors:  B A Cohen; P Colas; R Brent
Journal:  Proc Natl Acad Sci U S A       Date:  1998-11-24       Impact factor: 11.205
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