Literature DB >> 8937806

Peptide transporters.

V Ganapathy1, F H Leibach.   

Abstract

Proton-coupled peptide transporters found in animal cells are unique because of their energetics and their ability to accept a broad spectrum of chemically diverse peptides as substrates. The abundant expression of these transporters in the small intestine and the kidney indicates their importance in the maintenance of protein nutrition. There is also evidence for additional functions of the peptide transporters which are of physiological, pharmacological and clinical relevance.

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Year:  1996        PMID: 8937806     DOI: 10.1097/00041552-199609000-00003

Source DB:  PubMed          Journal:  Curr Opin Nephrol Hypertens        ISSN: 1062-4821            Impact factor:   2.894


  7 in total

Review 1.  Targeted prodrug design to optimize drug delivery.

Authors:  H K Han; G L Amidon
Journal:  AAPS PharmSci       Date:  2000

2.  Absorption of functionally active arginine-vasotocin in the frog small intestine.

Authors:  Yu V Natochin; N P Prutskova
Journal:  Dokl Biol Sci       Date:  2004 Jan-Feb

3.  Two oligopeptide transporters from Caenorhabditis elegans: molecular cloning and functional expression.

Authors:  Y J Fei; T Fujita; D F Lapp; V Ganapathy; F H Leibach
Journal:  Biochem J       Date:  1998-06-01       Impact factor: 3.857

4.  Competitive inhibition of glycylsarcosine transport by enalapril in rabbit renal brush border membrane vesicles: interaction of ACE inhibitors with high-affinity H+/peptide symporter.

Authors:  C J Lin; W Akarawut; D E Smith
Journal:  Pharm Res       Date:  1999-05       Impact factor: 4.200

5.  Activation of nicotinic receptor-induced postsynaptic responses to luteinizing hormone-releasing hormone in bullfrog sympathetic ganglia via a Na+-dependent mechanism.

Authors:  Y J Cao; Y Y Peng
Journal:  Proc Natl Acad Sci U S A       Date:  1998-10-13       Impact factor: 11.205

6.  Influence of overexpression of efflux proteins on the function and gene expression of endogenous peptide transporters in MDR-transfected MDCKII cell lines.

Authors:  Zhiying Wang; Dhananjay Pal; Ashaben Patel; Deep Kwatra; Ashim K Mitra
Journal:  Int J Pharm       Date:  2012-12-20       Impact factor: 5.875

7.  A tripeptide Diapin effectively lowers blood glucose levels in male type 2 diabetes mice by increasing blood levels of insulin and GLP-1.

Authors:  Jifeng Zhang; Changyong Xue; Tianqing Zhu; Anuradha Vivekanandan; Subramaniam Pennathur; Zhongmin Alex Ma; Y Eugene Chen
Journal:  PLoS One       Date:  2013-12-27       Impact factor: 3.240

  7 in total

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