Literature DB >> 8936545

Comparison of diclofenac and tenoxicam for postoperative analgesia with and without fentanyl in children undergoing adenotonsillectomy or tonsillectomy.

J E Mendham1, S J Mather.   

Abstract

127 children scheduled for elective tonsillectomy or adenotonsillectomy were studied. Anaesthesia was induced with propofol and maintained with a volatile agent. At induction the child received either rectal diclofenac 1 mg.kg-1 with or without fentanyl 0.75 microgram.kg-1 i.v., or intravenous tenoxicam 0.4 mg.kg-1 with or without fentanyl 0.75 microgram.kg-1 i.v. Blood loss was measured peroperatively. Nausea and vomiting scores, sedation scores and pain scores were recorded in the recovery room, at one, two, four and eight h postoperatively and at discharge. There were no significant differences in blood loss between the groups or between nausea and vomiting scores. Pain scores in the tenoxicam without fentanyl group were significantly higher in recovery (P < 0.05) than the diclofenac group without fentanyl and both fentanyl groups. This group required supplemental analgesia earlier although this was not significant. The pain scores in the diclofenac with fentanyl group were significantly lower at one h and four h than the group receiving diclofenac alone (P = 0.008 and 0.02 respectively).

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Year:  1996        PMID: 8936545     DOI: 10.1046/j.1460-9592.1996.d01-22.x

Source DB:  PubMed          Journal:  Paediatr Anaesth        ISSN: 1155-5645            Impact factor:   2.556


  5 in total

Review 1.  Nonsteroidal anti-inflammatory drugs and perioperative bleeding in paediatric tonsillectomy.

Authors:  Sharon R Lewis; Amanda Nicholson; Mary E Cardwell; Gretchen Siviter; Andrew F Smith
Journal:  Cochrane Database Syst Rev       Date:  2013-07-18

Review 2.  WITHDRAWN: Diclofenac for acute pain in children.

Authors:  Joseph F Standing; Imogen Savage; Deborah Pritchard; Marina Waddington
Journal:  Cochrane Database Syst Rev       Date:  2015-07-02

3.  Stability of diclofenac sodium oral suspensions packaged in amber polyvinyl chloride bottles.

Authors:  Ronald F Donnelly; Elena Pascuet; Carmen Ma; Régis Vaillancourt
Journal:  Can J Hosp Pharm       Date:  2010-01

4.  [Postoperative pain therapy after tonsillectomy in children. An observational study for 7 days].

Authors:  T Fösel; S Fötsch; O Ebeling
Journal:  HNO       Date:  2005-08       Impact factor: 1.284

Review 5.  Nonsteroidal anti-inflammatory drugs for postoperative pain: a focus on children.

Authors:  Hannu Kokki
Journal:  Paediatr Drugs       Date:  2003       Impact factor: 3.022

  5 in total

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