Literature DB >> 893362

Changes of DNA ligase in developing rat brain.

N Nakaya, Y Sawasaki, H Teraoka, H Nakajima, K Tsukada.   

Abstract

DNA ligase was isolated from rat brain and characterized. In developing rat brain the DNA ligase activities of the cerebellum increased after birth, at least 5 fold more than those of non-cerebellar parts. The DNA ligase activity in the cerebellum reached a maximum about 6 days after birth and then decreased towards maturation. The DNA ligase from the cerebellum can be fractionated into three molecular forms. Aging of the extracts leads to the conversion of the high molecular weight form into smaller weight forms.

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Year:  1977        PMID: 893362

Source DB:  PubMed          Journal:  J Biochem        ISSN: 0021-924X            Impact factor:   3.387


  2 in total

1.  DNA ligase I gene expression during differentiation and cell proliferation.

Authors:  A Montecucco; G Biamonti; E Savini; F Focher; S Spadari; G Ciarrocchi
Journal:  Nucleic Acids Res       Date:  1992-12-11       Impact factor: 16.971

2.  Base excision repair in the mammalian brain: implication for age related neurodegeneration.

Authors:  Peter Sykora; David M Wilson; Vilhelm A Bohr
Journal:  Mech Ageing Dev       Date:  2013-05-02       Impact factor: 5.432

  2 in total

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